Biphenyl

Biphenyl

SCHEMBL43102

C.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.90
MAPK1 P28482 2/20 0.56
TAAR1 Q96RJ0 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
NOTUM Q6P988 1/20 0.56
MMP3 P08254 1/20 0.56
BCL2L1 Q07817 1/20 0.56
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
ATM Q13315 1/20 0.50
SLC22A2 O15244 1/20 0.50
SLC22A1 O15245 1/20 0.50
SLC22A3 O75751 1/20 0.50
SLC6A4 P31645 1/20 0.50
MAOA P21397 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL4603524 1.00 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL10791683 1.00 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL29210065 1.00 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL29078567 1.00 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL1698235 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Methane SCHEMBL9326425 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL27572983 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL10806270 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL1498120 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL27333120 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11156 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119680626-B Hierarchical pore molecular sieve supported Cu-based bifunctional catalyst and preparation method and application thereof CHANGCHUN GOLD RESEARCH INSTITUTE Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12496564-B2 Dehydrogenation reaction apparatus and system including the same HYUNDAI MOTOR COMPANY (KR) 2025-12-16 US claimed
EP-4345088-B1 A PROCESS FOR PREPARING DI- AND POLYAMINES OF THE DIPHENYL METHANE SERIES COVESTRO DEUTSCHLAND AG (DE) 2025-10-22 EP claimed
CN-120058647-A Diphenyl methane derivative and its preparation method and application 中南大学 2025-05-30 CN claimed
CN-118703072-B Spray-type environment-friendly elastic putty and preparation method thereof 广州市中瀚创能新材料科技有限公司 2025-05-20 CN claimed
CN-115634655-B High-shear mixing reactor and preparation method of diphenylmethane series amine 万华化学集团股份有限公司 2025-05-16 CN claimed
CN-116606447-B Preparation and application of novel flower-like composite flame retardant based on Co/Cu-MOF 青岛理工大学 2025-04-25 CN claimed
CN-119798598-A Low-density high-strength high-damping rigid polyurethane foam and preparation method and application thereof 四川大学 2025-04-11 CN claimed
CN-119751323-A Preparation method of polythiol compound 益丰新材料股份有限公司 2025-04-04 CN claimed
CN-119746931-A Catalyst for preparing diphenyl methane, preparation thereof, diphenyl methane and synthesis method thereof 山东新和成药业有限公司 2025-04-04 CN claimed
US-4082806-A PREPARATION OF TETRAKETONES WRIGHT STATE UNIVERSITY (US) 1978-04-04 US claimed
US-4064079-A DISSOLVING POLYMER IN SOLVENT, PRECIPITATION MONSANTO COMPANY (US) 1977-12-20 US claimed
US-4025579-A ELASTOMERIC GRANULATES IN POLYURETHANE BINDER BAYER AKTIENGESELLSCHAFT (DT) 1977-05-24 US claimed
US-4022751-A ANTI-OXIDANT STABILIZERS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-05-10 US claimed
US-4003880-A Fabric dye stripping, separation and recovery of polyester MONSANTO COMPANY (US) 1977-01-18 US claimed
US-4003881-A Polyester polymer recovery from dyed polyester fabrics MONSANTO COMPANY (US) 1977-01-18 US claimed
US-3996223-A Process for the production of polyisocyanates of isocyanurate structure BAYER AKTIENGESELLSCHAFT (DT) 1976-12-07 US claimed
US-3976427-A Organic compounds SANDOZ LTD. (CH) 1976-08-24 US claimed
US-3965080-A Polymerization of monomers with alkaline earth metal organometallic compounds THE GENERAL TIRE & RUBBER COMPANY (US) 1976-06-22 US claimed
US-3960982-A NOVOLAKS HITACHI, LTD. (JA) 1976-06-01 US claimed