Sugi Predict

Sugi Predict / Compounds / Methane

Methane

Methane

SCHEMBL9326425

C.c1ccc2cccc-2cc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.82
▸ TAAR1 Q96RJ0 2/20 0.53
▸ MAPK1 P28482 2/20 0.53
▸ CYP1A2 P05177 1/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ TDP1 Q9NUW8 1/20 0.53
▸ NOTUM Q6P988 1/20 0.53
▸ MMP3 P08254 1/20 0.53
▸ BCL2L1 Q07817 1/20 0.53
▸ MAOA P21397 1/20 0.53
▸ RAB9A P51151 3/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ ATM Q13315 1/20 0.47
▸ SLC22A2 O15244 1/20 0.47
▸ SLC22A1 O15245 1/20 0.47
▸ SLC22A3 O75751 1/20 0.47
▸ SLC6A4 P31645 1/20 0.47
▸ NPC1 O15118 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL29078567 0.95 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
Biphenyl SCHEMBL43102 0.95 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
Biphenyl SCHEMBL29210065 0.95 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
Biphenyl SCHEMBL10791683 0.95 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
Biphenyl SCHEMBL4603524 0.95 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
SCHEMBL8463 0.95 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
SCHEMBL2468018 0.95 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
Benzene SCHEMBL6754211 0.95 ALDH1A1 (0.90) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
Biphenyl SCHEMBL10806270 0.91 ALDH1A1 (0.82) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4
Biphenyl SCHEMBL1698235 0.91 ALDH1A1 (0.82) ALDH1A1TAAR1MAPK1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011661-A — — None — — JP disclosed
JP-2011661-A — — None — — JP disclosed
CN-109363990-A A kind of old skin care compositions of removing wrinkle and resisting aging and its preparation method and application 广州姿三灏生物科技有限公司 2019-02-22 — — CN disclosed
CN-103596934-B Triazene compound and use thereof KUREHA CORP. (JP) 2015-08-19 — — CN disclosed
CN-104744409-A Method for manufacturing oxetane compound, method for manufacturing azolylmethylcyclopentanol compound, and intermediate compound KUREHA CORP 2015-07-01 — — CN disclosed
CN-104744315-A METHOD FOR MANUFACTURING OXETANE COMPOUND, METHOD FOR MANUFACTURING AZOLYLMETHYLCYCLOPENTANOL COMPOUND, AND INTERMEDIATE COMPOUND KUREHA CORP 2015-07-01 — — CN disclosed
CN-104529918-A Triazole compound and use thereof KUREHA CORP 2015-04-22 — — CN disclosed
EP-0338426-B1 Azulene methine dyes and recording material containing these dyes BASF AG (DE) 1994-03-02 — — EP disclosed
EP-0338426-A3 AZULENE METHINE DYES AND RECORDING MATERIAL CONTAINING THESE DYES BASF Aktiengesellschaft (DE) 1991-10-16 — — EP disclosed
JP-H0211661-A AZULENE METHINE DYESTUFF AND, OPTICAL RECORDING MEDIUM CONTAINING IT BASF AG 1990-01-16 — — JP disclosed
JP-H0211661-A AZULENE METHINE DYESTUFF AND, OPTICAL RECORDING MEDIUM CONTAINING IT BASF AG 1990-01-16 — — JP disclosed
EP-0338426-A2 Azulene methine dyes and recording material containing these dyes BASF Aktiengesellschaft (DE) 1989-10-25 — — EP disclosed