Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | MASP2 | O00187 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313109 | 0.91 | EPHX2 (0.48) | EPHX2NAMPTMASP2MEN1KMT2A | |
| SCHEMBL4309444 | 0.86 | NAMPT (0.47) | EPHX2NAMPTMASP2MEN1KMT2A | |
| SCHEMBL4310295 | 0.83 | CYP2C9 (0.46) | EPHX2NAMPTMASP2MEN1KMT2A | |
| SCHEMBL4308746 | 0.83 | NAMPT (0.41) | EPHX2NAMPTMASP2MEN1KMT2A | |
| SCHEMBL4309422 | 0.82 | NAMPT (0.43) | EPHX2NAMPTMASP2HDAC1 | |
| Hydrochloric Acid SCHEMBL4310570 | 0.82 | NAMPT (0.40) | EPHX2NAMPTMASP2MEN1KMT2A | |
| SCHEMBL4305812 | 0.79 | NAMPT (0.46) | NAMPTMASP2MEN1KMT2AFURIN | |
| SCHEMBL3154590 | 0.79 | EPHX2 (0.47) | EPHX2NAMPTMASP2 | |
| SCHEMBL4303211 | 0.78 | NAMPT (0.46) | EPHX2NAMPTMASP2GABRPGABRD | |
| SCHEMBL4314574 | 0.77 | MASP2 (0.48) | NAMPTMASP2MEN1KMT2AFURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |