⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088942 | 0.67 | — | — | |
| SCHEMBL1076627 | 0.62 | — | — | |
| SCHEMBL4723369 | 0.62 | — | — | |
| Dimethylamine SCHEMBL1760836 | 0.61 | — | — | |
| SCHEMBL3221482 | 0.61 | — | — | |
| SCHEMBL24501930 | 0.59 | — | — | |
| SCHEMBL28225821 | 0.53 | INMT (0.39) | — | |
| Benzene SCHEMBL27922842 | 0.52 | TSHR (0.43) | — | |
| Benzene SCHEMBL890697 | 0.52 | — | — | |
| Benzene SCHEMBL28192913 | 0.52 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1483320-A | Heterocyclic ring contained methylamine cyanoacrylate compound and weeding activity | 南开大学 | 2004-03-24 | — | — | CN | claimed |
| EP-3519411-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS | MUTABILIS (FR) | 2022-06-22 | — | — | EP | disclosed |
| WO-2018174650-A9 | PYRROLO-PYRIDINE DERIVATIVE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF PROTEIN KINASE-RELATED DISEASES | 재단법인 대구경북첨단의료산업진흥재단 | 2020-01-02 | — | — | WO | disclosed |
| CN-109293523-A | A kind of ionic cross-linking monomer, Its Preparation Method And Use | 世晟博（深圳）科技有限公司 | 2019-02-01 | — | — | CN | disclosed |
| WO-2018075479-A1 | SYNTHESIS AND CHARACTERIZATION OF RU ALKYLIDENE COMPLEXES | MATERIA, INC. (US) | 2018-04-26 | — | — | WO | disclosed |
| WO-2018060481-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS | MUTABILIS (FR) | 2018-04-05 | — | — | WO | disclosed |
| EP-3301094-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN PREVENTING OR TREATING BACTERIAL INFECTIONS | Mutabilis (FR) | 2018-04-04 | — | — | EP | disclosed |
| CN-102118969-B | Diaminopyridine, diaminopyrimidine and diaminopyridazine modulators of the histamine H4 receptor | 詹森药业有限公司 | 2017-03-08 | — | — | CN | disclosed |
| EP-1322642-B1 | Pharmaceutically active sulfonamide derivatives bearing both lipophilic and ionisable moieties as inhibitors of Protein Jun-kinases | MERCK SERONO SA (CH) | 2013-09-04 | — | — | EP | disclosed |
| US-8431695-B2 | Pyrrolo[2,1-f][1,2,4]triazin-4-ylamines IGF-1R kinase inhibitors for the treatment of cancer and other hyperproliferative diseases | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-30 | — | — | US | disclosed |
| EP-0402752-A1 | N-heteroaryl-purin-6-amines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0397040-A2 | N-heteroaryl-4-quinolinamines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4916135-A | ANALGESICS, ALZHEIMER*S | HOECHST ROUSSEL PHARMACEUTICALS INC. (US) | 1990-04-10 | — | — | US | disclosed |
| US-4914103-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-04-03 | — | — | US | disclosed |
| US-4900742-A | N-(pyrrol-1-yl)pyridinamine compounds having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1990-02-13 | — | — | US | disclosed |
| EP-0352629-A2 | Pyrido [3,4-f]pyrrolo[1,2-b][1,2,5]triazepines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1990-01-31 | — | — | EP | disclosed |
| US-4879382-A | ANTIDEPRESSANT, ANALGESIC, ANTIINFLAMMATORY, MEMORY ENHANCER | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-11-07 | — | — | US | disclosed |
| US-4792562-A | N-(pyrrol-1-yl)pyridinamines having memory enhancing activity | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-12-20 | — | — | US | disclosed |
| US-4752610-A | N-(pyrrol-1-yl)pyridinamines having memory enhancing properties | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-06-21 | — | — | US | disclosed |
| EP-0226099-A2 | N-(pyrrol-1-yl)pyridinamines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1987-06-24 | — | — | EP | disclosed |