SCHEMBL431273

SCHEMBL431273

CC[Si](Oc1ccccc1)(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.42
LTA4H P09960 5/20 0.41
TSHR P16473 1/20 0.39
KCNA3 P22001 1/20 0.39
CHRNB2 P17787 2/20 0.38
CHRNB4 P30926 2/20 0.38
CHRNA3 P32297 2/20 0.38
CHRNA7 P36544 2/20 0.38
CHRNA4 P43681 2/20 0.38
CA5A P35218 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
TP53 P04637 1/20 0.36
KCNH2 Q12809 1/20 0.35
LMNA P02545 1/20 0.35
HTR1D P28221 1/20 0.35
HTR1B P28222 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1482787 0.91 LTA4H (0.39) CA4LTA4HTSHRKCNA3CHRNB2
SCHEMBL6698487 0.89 MAOA (0.39) CA4LTA4HLMNA
SCHEMBL1608663 0.89 CA4 (0.42) CA4LTA4HTSHRKCNA3CHRNB2
SCHEMBL10567481 0.89 CA4 (0.42) CA4LTA4HTSHRKCNA3CHRNB2
SCHEMBL16411946 0.88 CA4 (0.38) CA4LTA4HTSHRKCNA3CHRNB2
SCHEMBL19816431 0.87 LTA4H (0.41) CA4LTA4HTSHRKCNA3CHRNB2
SCHEMBL31187708 0.87 LTA4H (0.41) CA4LTA4HTSHRKCNA3CHRNB2
SCHEMBL1482361 0.85 LTA4H (0.35) CA4LTA4HTSHRKCNA3CHRNB2
SCHEMBL1481841 0.83 LTA4H (0.34) CA4LTA4HTSHRKCNA3CHRNB2
SCHEMBL977952 0.82 KCNA3 (0.46) CA4LTA4HTSHRKCNA3CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 770 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11059920-B2 Process for producing high cis-1,4-polydiene with lanthanide-based catalyst compositions BRIDGESTONE CORPORATION (JP) 2021-07-13 US claimed
US-20190169330-A1 Process For Producing High Cis-1,4-Polydiene With Lanthanide-Based Catalyst Compositions BRIDGESTONE CORPORATION (JP) 2019-06-06 US claimed
EP-3491030-A1 PROCESS FOR PRODUCING HIGH CIS-1,4-POLYDIENE WITH LANTHANIDE-BASED CATALYST COMPOSITIONS Bridgestone Corporation (JP) 2019-06-05 EP claimed
WO-2018022994-A1 PROCESS FOR PRODUCING HIGH CIS-1,4-POLYDIENE WITH LANTHANIDE-BASED CATALYST COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2018-02-01 WO claimed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US claimed
US-7709551-B2 Coating composition for film with low refractive index and film prepared therefrom LG CHEM, LTD. (KR) 2010-05-04 US claimed
WO-2006129973-A9 COATING COMPOSITION FOR FILM WITH LOW REFRACTIVE INDEX AND FILM PREPARED THEREFROM LG CHEM, LTD. (KR) 2010-01-21 WO claimed
US-7582712-B1 Alpha-olefins polymerization catalyst FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2009-09-01 US claimed
US-7528199-B2 Conjugated-diolefin (co)polymer rubber and process for producing the same JSR CORPORATION (JP) 2009-05-05 US claimed
US-20080090926-A1 Coating Composition for Film with Low Refractive Index and Film Prepared Therefrom LG CHEM, LTD. (KR) 2008-04-17 US claimed
US-20040127070-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. 2004-07-01 US claimed
WO-2004027110-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES ARCH SPECIALTY CHEMICALS, INC. (US) 2004-04-01 WO claimed
EP-0890580-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORP (JP) 2003-09-17 EP claimed
US-6228908-B1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds BRIDGESTONE CORPORATION (JP) 2001-05-08 US claimed
EP-0447066-B2 Pneumatic tyres BRIDGESTONE CORP (JP) 2000-08-16 EP claimed
US-6008295-A FIRST COUPLING THE LIVING DIENE POLYMER OR COPOLYMER CHAINS OBTAINED BY ANIONIC POLYMERIZATION WITH A TIN HALIDE COUPLING AGENT AND THEN TERMINATING THE REMAINING LIVING POLYMER OR COPOLYMER CHAINS WITH A HYDROCARBOXYSILANE; TIRE TREADS BRIDGESTONE CORPORATION (JP) 1999-12-28 US claimed
EP-0890580-A1 Diene polymers and copolymers incorporating partial coupling and terminals formed from hydrocarboxysilane compounds Bridgestone Corporation (JP) 1999-01-13 EP claimed
US-5409969-A Comprising silica filler, carbon black, silane coupler, living polymer of butadiene-styrene BRIDGESTONE CORPORATION (JP) 1995-04-25 US claimed
EP-0447066-A1 Pneumatic tyres Bridgestone Corporation (JP) 1991-09-18 EP claimed
US-5017636-A Also containing polyisoprene, natural rubber, butadiene-styrene copolymer, wear and heat resistance, resilience JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-05-21 US claimed