Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713985 | 0.78 | S1PR1 (0.56) | CYP1A2S1PR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL225237 | 0.77 | BRD4 (0.39) | CYP1A2NPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL28706245 | 0.76 | ALDH1A1 (0.35) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL713411 | 0.74 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3858280 | 0.73 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL957492 | 0.70 | NPC1 (0.57) | S1PR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4313506 | 0.70 | NPC1 (0.42) | CNR2CYP1A2S1PR1HDAC6NPC1 | |
| SCHEMBL17344108 | 0.69 | KDM4E (0.54) | CYP1A2NPC1CASP3RAB9ASMN1; SMN2 | |
| SCHEMBL2612639 | 0.68 | NPC1 (0.49) | CYP1A2HDAC6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16543489 | 0.68 | KDM4E (0.50) | CYP1A2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |