SCHEMBL4313674

SCHEMBL4313674

Fc1nc(F)c2c(F)c(F)c(F)c(F)c2c1F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443238 0.83 MEN1 (0.32) MEN1MAPTHTTKMT2A
SCHEMBL188694 0.75 MEN1 (0.41) MEN1MAPTHTTKMT2A
SCHEMBL10027668 0.75
SCHEMBL3146554 0.75
SCHEMBL245064 0.71
SCHEMBL20247534 0.69
SCHEMBL4308426 0.67 KDM4E (0.33) MEN1MAPTHTTKMT2A
SCHEMBL5873399 0.67
SCHEMBL3446785 0.67
SCHEMBL979901 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090221787-A1 Production Of Monomer, Oligomer And Polymer Phosphonic Acid Esters And Phosphonic And Sulphonic Acids By A Nucleophile Aromatic Substitution HARING THOMAS 2009-09-03 US claimed
EP-1931608-A1 PRODUCTION OF MONOMER, OLIGOMER AND POLYMER PHOSPHONIC ACID ESTERS AND PHOSPHONIC AND SULPHONIC ACIDS BY A NUCLEOPHILE AROMATIC SUBSTITUTION Universität Stuttgart (DE) 2008-06-18 EP claimed
WO-2007006300-A1 PRODUCTION OF MONOMER, OLIGOMER AND POLYMER PHOSPHONIC ACID ESTERS AND PHOSPHONIC AND SULPHONIC ACIDS BY A NUCLEOPHILE AROMATIC SUBSTITUTION Universität Stuttgart (DE) 2007-01-18 WO claimed
WO-2006066569-A2 IONOMERS AND IONOMER BLENDS BASED ON PARTIALLY FLUORINATED POLY(HETERO)ARYLS HÄRING, Thomas (DE) 2006-06-29 WO claimed
CN-108017582-B Synthetic method of bromine-containing 1, 3-isoquinolinedione derivative 西北师范大学 2020-08-11 CN disclosed
EP-1889891-B1 Luminescence device and display apparatus CANON KK (JP) 2017-11-22 EP disclosed
US-20150076478-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KK (JP) 2015-03-19 US disclosed
US-20150076478-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KK (JP) 2015-03-19 US disclosed
US-8920943-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2014-12-30 US disclosed
US-8920943-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2014-12-30 US disclosed
US-7687155-B2 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2010-03-30 US disclosed
US-7687155-B2 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2010-03-30 US disclosed
US-7527879-B2 Luminescence device and display apparatus CANON KABUSHIKI KAISHA (JP) 2009-05-05 US disclosed
EP-1889891-A2 Luminescence device and display apparatus Canon Kabushiki Kaisha (JP) 2008-02-20 EP disclosed
EP-1881050-A2 Luminescence device and display apparatus Canon Kabushiki Kaisha (JP) 2008-01-23 EP disclosed
US-20070216294-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2007-09-20 US disclosed
US-20070216294-A1 LUMINESCENCE DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2007-09-20 US disclosed
US-20070212570-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2007-09-13 US disclosed
US-20070212570-A1 Comprises iridium complexes, coordination compounds; red phosphorescence; high efficiency CANON KABUSHIKI KAISHA (JP) 2007-09-13 US disclosed
WO-2006066569-A2 IONOMERS AND IONOMER BLENDS BASED ON PARTIALLY FLUORINATED POLY(HETERO)ARYLS HÄRING, Thomas (DE) 2006-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221787-A1 Production Of Monomer, Oligomer And Polymer Phosphonic Acid Esters And Phosphonic And Sulphonic Acids By A Nucleophile Aromatic Substitution PFKFB2, PFKFB4, PFKFB1 MEN1 2439/4885MAPT 3137/4885HTT 408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.