Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | MIF | P14174 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | GAPDH | P04406 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13749990 | 0.99 | NPC1 (0.55) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL13750139 | 0.94 | NPC1 (0.55) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL13750220 | 0.92 | MIF (0.59) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL5590725 | 0.92 | MIF (0.58) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL13870277 | 0.90 | MIF (0.57) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL13749920 | 0.89 | MAPT (0.50) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL13749929 | 0.88 | NPC1 (0.51) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL13749903 | 0.88 | RAB9A (0.49) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL13750126 | 0.84 | RAB9A (0.47) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL5934890 | 0.83 | MIF (0.53) | NPC1MIFRAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569694-B2 | Coumarin compound, material for light emitting device and organic electroluminescent device | CHISSO CORPORATION (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7569694-B2 | Coumarin compound, material for light emitting device and organic electroluminescent device | CHISSO CORPORATION (JP) | 2009-08-04 | — | — | US | disclosed |
| US-7569694-B2 | Coumarin compound, material for light emitting device and organic electroluminescent device | CHISSO CORPORATION (JP) | 2009-08-04 | — | — | US | disclosed |
| JP-2007204395-A | COUMARIN-BASED COMPOUND, MATERIAL FOR LIGHT-EMITTING ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT | CHISSO CORP | 2007-08-16 | — | — | JP | disclosed |
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | JNC CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | JNC CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | JNC CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | TRPA1, CYP3A4, UGT1A10 | NPC1 342/4885MIF 1471/4885RAB9A 4254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.