Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.69 |
| ▸ | RET | P07949 | 1/20 | 0.69 |
| ▸ | KDR | P35968 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16823312 | 0.99 | EGFR (0.70) | EGFRRETKDRSIGMAR1BCHE | |
| SCHEMBL433900 | 0.96 | EGFR (0.71) | EGFRRETKDRSIGMAR1BCHE | |
| SCHEMBL13186952 | 0.86 | EGFR (0.69) | EGFRRETKDR | |
| SCHEMBL12678185 | 0.85 | EGFR (0.80) | EGFRRETKDR | |
| SCHEMBL12792587 | 0.83 | EGFR (0.72) | EGFRRETKDR | |
| SCHEMBL28031602 | 0.82 | EGFR (0.74) | EGFRRETKDR | |
| SCHEMBL8786556 | 0.81 | SIGMAR1 (0.65) | SIGMAR1BCHEACHE | |
| SCHEMBL432003 | 0.81 | BCHE (0.75) | EGFRRETKDRBCHEACHE | |
| SCHEMBL8787025 | 0.81 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL8788283 | 0.81 | SIGMAR1 (1.00) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9642854-B2 | Flavanoid compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-09 | — | — | US | disclosed |
| US-9642854-B2 | Flavanoid compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-09 | — | — | US | disclosed |
| US-9642854-B2 | Flavanoid compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-09 | — | — | US | disclosed |
| US-20150174135-A1 | FLAVANOID COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2015-06-25 | — | — | US | disclosed |
| US-20150174135-A1 | FLAVANOID COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2015-06-25 | — | — | US | disclosed |
| US-20150174135-A1 | FLAVANOID COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2015-06-25 | — | — | US | disclosed |
| US-8969384-B2 | Flavonoid compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-03-03 | — | — | US | disclosed |
| US-8969384-B2 | Flavonoid compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-03-03 | — | — | US | disclosed |
| US-8969384-B2 | Flavonoid compounds and process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-03-03 | — | — | US | disclosed |
| US-20120022062-A1 | Flavanoid Compounds and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | US | disclosed |
| US-20120022062-A1 | Flavanoid Compounds and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | US | disclosed |
| US-20120022062-A1 | Flavanoid Compounds and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174135-A1 | FLAVANOID COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | F2, FOXM1, HRH2 | EGFR 3521/4885RET 2552/4885KDR 4551/4885 |
| US-20120022062-A1 | Flavanoid Compounds and Process for Preparation Thereof | F2, FOXM1, HRH2 | EGFR 3521/4885RET 2552/4885KDR 4551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.