Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 5/20 | 0.33 |
| ▸ | CASP7 | P55210 | 4/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942325 | 1.00 | FKBP1A (0.35) | FKBP1AGAACASP3CASP7CASP1 | |
| SCHEMBL3929383 | 0.92 | FKBP1A (0.37) | FKBP1AGAACASP3CASP7CASP1 | |
| SCHEMBL4060012 | 0.91 | CASP3 (0.36) | FKBP1AGAACASP3CASP7CASP1 | |
| SCHEMBL4060017 | 0.91 | CASP3 (0.36) | FKBP1AGAACASP3CASP7CASP1 | |
| SCHEMBL3940425 | 0.88 | FKBP1A (0.34) | FKBP1AGAACASP3CASP7 | |
| SCHEMBL3932125 | 0.87 | FKBP1A (0.37) | FKBP1AGAACASP3CASP7CASP1 | |
| SCHEMBL3942855 | 0.86 | GAA (0.36) | FKBP1AGAACASP3CASP7ALDH1A1 | |
| SCHEMBL4314277 | 0.83 | GAA (0.35) | FKBP1AGAACASP3CASP7CASP1 | |
| SCHEMBL4050149 | 0.80 | CNR2 (0.36) | FKBP1AGAAALDH1A1LMNAKMT2A | |
| SCHEMBL3930886 | 0.74 | CYP2C9 (0.36) | GAACASP3CASP7LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044059-A1 | 2,5-DISUBSTITUTED PIPERIDINES | Speedel Experimenta AG (CH) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007141318-A1 | 2,5-DISUBSTITUTED PIPERIDINES | SPEEDEL EXPERIMENTA AG (CH) | 2007-12-13 | — | — | WO | disclosed |