Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 5/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | GUSB | P08236 | 2/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623879 | 1.00 | GNAO1 (0.41) | GNAO1GNAI3GNAI1ALOX5TSHR | |
| SCHEMBL6397047 | 0.98 | GNAO1 (0.39) | GNAO1GNAI3GNAI1ALOX5TSHR | |
| Hydrochloric Acid SCHEMBL14956779 | 0.96 | GNAO1 (0.38) | GNAO1GNAI3GNAI1ALOX5TSHR | |
| SCHEMBL11293775 | 0.91 | MEN1 (0.32) | GNAO1GNAI3GNAI1 | |
| SCHEMBL9186089 | 0.82 | GNAO1 (0.41) | GNAO1GNAI3GNAI1ALOX5TSHR | |
| SCHEMBL28480879 | 0.78 | L3MBTL1 (0.43) | GNAO1GNAI3GNAI1ALOX5 | |
| SCHEMBL7026849 | 0.78 | MEN1 (0.35) | GNAO1GNAI3GNAI1TSHR | |
| SCHEMBL13764651 | 0.74 | GNAO1 (0.38) | GNAO1GNAI3GNAI1ALOX5BCHE | |
| SCHEMBL7478832 | 0.73 | HRH3 (0.62) | GNAO1GNAI3GNAI1BCHEGUSB | |
| SCHEMBL768306 | 0.73 | HRH3 (0.62) | GNAO1GNAI3GNAI1BCHEGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009135813-A1 | DEGRADABLE MATERIAL | BASF SE (DE) | 2009-11-12 | — | — | WO | disclosed |