SCHEMBL431545

SCHEMBL431545

CCC[Si]1(C)OC(C)(C)C[Si](C)(C)[Si]1(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28904258 0.93
SCHEMBL3874184 0.83
SCHEMBL4940020 0.80
SCHEMBL28916770 0.80
SCHEMBL4941497 0.79
SCHEMBL6658152 0.79
SCHEMBL3965447 0.78
SCHEMBL2522524 0.78
SCHEMBL1696074 0.74
SCHEMBL4940551 0.74 HRH3 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117883308-A Cosmetic or dermatological composition comprising a merocyanine and an oily phase comprising at least one alkyl or alkylene carbonate 莱雅公司 2024-04-16 CN disclosed
CN-116919852-A Cosmetic or dermatological composition comprising a merocyanine and an acrylic polymer 莱雅公司 2023-10-24 CN disclosed
CN-110087609-B Water-in-oil emulsion containing baicalin, xanthine base, vitamin B3, and polyvalent metal cation salt 莱雅公司 2022-11-15 CN disclosed
EP-2022812-B1 POLYETHER-MODIFIED ORGANOPOLYSILOXANE, DIORGANOPOLYSILOXANE-POLYETHER BLOCK COPOLYMER, THEIR PRODUCTION METHODS, AND COSMETIC PREPARATION DOW CORNING TORAY CO LTD (JP) 2014-04-23 EP disclosed
EP-2595626-A1 COMBINATION OF SILOXANE AND ACTIVE INGREDIENT FOR TREATING DENTAL DISORDER Bayer Innovation GmbH (DE) 2013-05-29 EP disclosed
EP-2575970-A2 COSMETIC COMPOSITION BASED ON A SUPRAMOLECULAR POLYMER AND A SILICONE COMPOUND L'Oréal (FR) 2013-04-10 EP disclosed
EP-2575751-A1 COSMETIC COMPOSITION COMPRISING AN OIL AND A POLYMER BOTH BEARING A HYDROGEN-BOND-GENERATING JOINING GROUP, AND COSMETIC TREATMENT PROCESS L'Oréal (FR) 2013-04-10 EP disclosed
EP-2575752-A1 COSMETIC COMPOSITION COMPRISING A POLYSILOXANE AND A POLYMER BOTH BEARING A HYDROGEN-BOND-GENERATING JOINING GROUP, AND COSMETIC TREATMENT PROCESS L'Oréal (FR) 2013-04-10 EP disclosed
WO-2012010478-A1 COMBINATION OF SILOXANE AND ACTIVE INGREDIENT FOR TREATING DENTAL DISORDER BAYER INNOVATION GMBH (DE) 2012-01-26 WO disclosed
WO-2011147696-A1 COSMETIC COMPOSITION COMPRISING AN OIL AND A POLYMER BOTH BEARING A HYDROGEN-BOND-GENERATING JOINING GROUP, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2011-12-01 WO disclosed
WO-2011148324-A2 COSMETIC COMPOSITION BASED ON A SUPRAMOLECULAR POLYMER AND A SILICONE COMPOUND L'OREAL (FR) 2011-12-01 WO disclosed
WO-2011147697-A1 COSMETIC COMPOSITION COMPRISING A POLYSILOXANE AND A POLYMER BOTH BEARING A HYDROGEN-BOND-GENERATING JOINING GROUP, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2011-12-01 WO disclosed
US-8034891-B2 Polyether-modified organopolysiloxane, diorganopolysiloxane-polyether block copolymer, their production methods, and cosmetic preparation DOW CORNING TORAY COMPANY, LTD. (JP) 2011-10-11 US disclosed
EP-2296667-A2 SILICONE COMPOSITION Momentive Performance Materials Inc. (US) 2011-03-23 EP disclosed
US-20100036062-A1 Polyether-Modified Organopolysiloxane, Diorganopolysiloxane-Polyether Block Copolymer, Their Production Methods, and Cosmetic Preparation DOW TORAY CO., LTD. (JP) 2010-02-11 US disclosed
WO-2010005538-A2 SILICONE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-01-14 WO disclosed
EP-2022812-A1 POLYETHER-MODIFIED ORGANOPOLYSILOXANE, DIORGANOPOLYSILOXANE-POLYETHER BLOCK COPOLYMER, THEIR PRODUCTION METHODS, AND COSMETIC PREPARATION Dow Corning Toray Co., Ltd. (JP) 2009-02-11 EP disclosed
EP-1472263-A1 USE OF SILOXANES AS EVAPORABLE SUPPORTS GE Bayer Silicones GmbH &amp; Co. KG (DE) 2004-11-03 EP disclosed
WO-2003042221-A1 USE OF SILOXANES AS EVAPORABLE SUPPORTS GE BAYER SILICONES GMBH & CO. KG (DE) 2003-05-22 WO disclosed