Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 6/20 | 0.44 |
| ▸ | STS | P08842 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417359 | 0.82 | ALDH1A1 (0.48) | HSD17B3PTPN2PTPN1CDC25BHTT | |
| SCHEMBL28413752 | 0.82 | ALDH1A1 (0.48) | HSD17B3PTPN2PTPN1CDC25BHTT | |
| SCHEMBL28417411 | 0.82 | ALDH1A1 (0.48) | HSD17B3PTPN2PTPN1CDC25BHTT | |
| SCHEMBL334229 | 0.80 | ESR1 (0.51) | HSD17B3PTPN2PTPN1CDC25BHTT | |
| SCHEMBL10730928 | 0.77 | GAA (0.54) | HSD17B3 | |
| SCHEMBL10609655 | 0.76 | HSD17B3 (0.54) | HSD17B3STSCA2HTTFFAR1 | |
| SCHEMBL27339010 | 0.75 | ALDH1A1 (0.47) | PTPN2PTPN1CDC25BKDM4EPOLB | |
| SCHEMBL28835963 | 0.74 | THRA (0.47) | HSD17B3STSCA2HTTFFAR1 | |
| SCHEMBL13509256 | 0.74 | HSD17B3 (0.67) | HSD17B3STSCDC25B | |
| SCHEMBL2655962 | 0.74 | HSD17B3 (0.67) | HSD17B3STSCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |