SCHEMBL43158

SCHEMBL43158

O=S(=O)(O)c1cccc2cccc(Nc3ccccc3)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 1.00
TTR P02766 1/20 1.00
CCNA2 P20248 1/20 1.00
CDK2 P24941 1/20 1.00
MAPK14 Q16539 1/20 1.00
NR4A1 P22736 1/20 0.97
SNCA P37840 3/20 0.67
CHAT P28329 1/20 0.67
FABP1 P07148 1/20 0.62
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
THRB P10828 1/20 0.52
MAPT P10636 3/20 0.51
ALDH1A1 P00352 2/20 0.51
KDM4E B2RXH2 2/20 0.51
GAA P10253 2/20 0.51
RECQL P46063 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
NSD2 O96028 2/20 0.51
CASP6 P55212 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381891 1.00 FABP4 (1.00) FABP4TTRCCNA2CDK2MAPK14
Ammonia Solution, Strong SCHEMBL592279 0.98 NR4A1 (1.00) FABP4TTRCCNA2CDK2MAPK14
Ammonia Solution, Strong SCHEMBL592280 0.98 NR4A1 (1.00) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL6654772 0.98 FABP4 (0.97) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL10353163 0.98 FABP4 (0.97) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL1786500 0.98 FABP4 (0.97) FABP4TTRCCNA2CDK2MAPK14
Ammonia Solution, Strong SCHEMBL31666356 0.97 NR4A1 (0.97) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL7522280 0.92 FABP4 (0.84) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL29837420 0.92 CDK2 (0.84) FABP4TTRCCNA2CDK2MAPK14
Questiomycin B SCHEMBL20817145 0.88 TTR (0.78) FABP4TTRCCNA2CDK2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7059 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260140108-A1 EXTRACTION ROD AND PREPARATION METHOD THEREOF, AND METHOD FOR DETECTING 25-HYDROXYVITAMIN D INNOVATION CENTER OF YANGTZE RIVER DELTA ZJU (CN) 2026-05-21 US claimed
EP-4427033-B1 METHOD FOR QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES PAIA BIOTECH GMBH (DE) 2026-05-20 EP claimed
US-12630857-B2 Biological indicator for determining the efficacy of a steam or heat sterilization process and its method of use TERRAGENE LLC (US) 2026-05-19 US claimed
US-20260083363-A1 LUMINESCENT ENZYME-BASED SENSORS TERUMO CARDIOVASCULAR SYS CORP (US) 2026-03-26 US claimed
EP-4682539-A1 METHOD FOR DETECTING MISFOLDED ALPHA-SYNUCLEIN PROTEIN IN BIOLOGICAL SAMPLES TO DETERMINE THE PRESENCE OF SYNUCLEINOPATHIES IN AN INDIVIDUAL Modag GmbH (DE) 2026-01-21 EP claimed
EP-4662484-A1 MULTISENSOR ARRAYS, MULTISENSOR SYSTEMS AND RELATED METHODS Linxens Holding (FR) 2025-12-17 EP claimed
US-12421447-B2 Fluorescent metal organic frameworks (MOFs) for drilling depth correlation and waterfront mapping SAUDI ARABIAN OIL COMPANY (SA) 2025-09-23 US claimed
US-20250269370-A1 MICROFLUIDIC URINE ALBUMIN/CREATININE CHIP (uACR-CHIP) FOR CHRONIC KIDNEY DISEASE EVALUATION UNIVERSITY OF MANITOBA (CA) 2025-08-28 US claimed
CN-120082345-A Perovskite material, perovskite solar cell and preparation method of perovskite material 陕西国防工业职业技术学院 2025-06-03 CN claimed
CN-113454099-B Detection of colonography in vivo using near infrared peptides targeting over-expression of cMET 密歇根大学董事会 2025-05-27 CN claimed
US-4110076-A IN UNEXTRACTED BLOOD SERUM MALLINCKRODT, INC. (US) 1978-08-29 US claimed
US-4108974-A ANTIBODIES BOUND TO POLYACRYLAMIDE BIO-RAD LABORATORIES, INC. (US) 1978-08-22 US claimed
US-4107284-A Radioimmunoassay procedure using a stabilized complex SULTANIAN ISHKHAN V 1978-08-15 US claimed
US-4069016-A Assay for bilirubin EASTMAN KODAK COMPANY (US) 1978-01-17 US claimed
US-4052504-A IMMUNOASSAY CORNING GLASS WORKS (US) 1977-10-04 US claimed
US-4049499-A Microbial medium having fluorescent growth indicator CORNING GLASS WORKS (US) 1977-09-20 US claimed
US-4046870-A IMMUNOASSAY CORNING GLASS WORKS (US) 1977-09-06 US claimed
US-4039387-A 8-ANILINO-1-NAPHTALENE SULFONIC ACID CORNING GLASS WORKS (US) 1977-08-02 US claimed
US-4018883-A PRECIPITATION OF ANTIBODIES WITH POLYOXYETHYLENE GLYCOL NICHOLS INSTITUTE FOR ENDOCRINOLOGY (US) 1977-04-19 US claimed
US-3995019-A FOR RADIOIMMUNOASSAY CONSISTING OF A SPECIFIC ANTIBODY RADIOLABELED, ANTIGEN, POLYETHYLENE GLYCOL, AND GAMMA GLOBULIN BAXTER TRAVENOL LABORATORIES, INC. (US) 1976-11-30 US claimed