SCHEMBL1786500

SCHEMBL1786500

O=S(=O)(O)c1cccc2cccc(Nc3ccccc3)c12.[Na]

nearest known ligand 0.97

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 0.97
TTR P02766 1/20 0.97
CCNA2 P20248 1/20 0.97
CDK2 P24941 1/20 0.97
MAPK14 Q16539 1/20 0.97
NR4A1 P22736 1/20 0.94
SNCA P37840 3/20 0.65
CHAT P28329 1/20 0.65
FABP1 P07148 1/20 0.61
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
THRB P10828 1/20 0.54
MAPT P10636 3/20 0.50
ALDH1A1 P00352 2/20 0.50
NSD2 O96028 2/20 0.50
CASP6 P55212 2/20 0.50
KDM4E B2RXH2 2/20 0.50
GAA P10253 2/20 0.50
RECQL P46063 2/20 0.50
TDP1 Q9NUW8 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381891 0.98 FABP4 (1.00) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL43158 0.98 FABP4 (1.00) FABP4TTRCCNA2CDK2MAPK14
Ammonia Solution, Strong SCHEMBL592279 0.97 NR4A1 (1.00) FABP4TTRCCNA2CDK2MAPK14
Ammonia Solution, Strong SCHEMBL592280 0.97 NR4A1 (1.00) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL10353163 0.97 FABP4 (0.97) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL6654772 0.97 FABP4 (0.97) FABP4TTRCCNA2CDK2MAPK14
Ammonia Solution, Strong SCHEMBL31666356 0.95 NR4A1 (0.97) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL29837420 0.90 CDK2 (0.84) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL7522280 0.90 FABP4 (0.84) FABP4TTRCCNA2CDK2MAPK14
SCHEMBL10438683 0.87 TTR (0.74) FABP4TTRCCNA2CDK2MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230358677-A1 Reversible Excited-State Photoacids and Photobases as Dynamic Fluorescence Sensors of Protonic Species CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-11-09 US claimed
CN-118119848-A Fluorescent cellulose particles 旭化成株式会社 2024-05-31 CN disclosed
US-20230358677-A1 Reversible Excited-State Photoacids and Photobases as Dynamic Fluorescence Sensors of Protonic Species CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-11-09 US disclosed
CN-115317532-A Application of rosemary alcohol extract in inhibiting glycosylated end products AGEs induced by glyoxal GO 杭州师范大学 2022-11-11 CN disclosed
CN-107047925-B Method for efficiently and mildly reducing ovalbumin allergenicity 西北农林科技大学 2020-05-22 CN disclosed
CN-106501535-B A kind of kit of the compound releasing agent of ANS salt and detection Blood cortisol 迪瑞医疗科技股份有限公司 2018-11-09 CN disclosed
CN-107362354-A A kind of oral insulin nanometer formulation and preparation method thereof 复旦大学 2017-11-21 CN disclosed
CN-106501535-A A kind of compound releasing agent of ANS salt and the kit for detecting Blood cortisol 长春迪瑞医疗科技股份有限公司 2017-03-15 CN disclosed
US-8772540-B2 Thermal responsive molecule KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2014-07-08 US disclosed
US-20110124916-A1 THERMAL RESPONSIVE MOLECULE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2011-05-26 US disclosed
US-3995019-A FOR RADIOIMMUNOASSAY CONSISTING OF A SPECIFIC ANTIBODY RADIOLABELED, ANTIGEN, POLYETHYLENE GLYCOL, AND GAMMA GLOBULIN BAXTER TRAVENOL LABORATORIES, INC. (US) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124916-A1 THERMAL RESPONSIVE MOLECULE HEATR1, HEATR6, HSPH1 FABP4 1684/4885TTR 512/4885CCNA2 363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.