Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 8/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 5/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876914 | 0.83 | MAPT (0.41) | MAPTCA2CA1FAAHMAPK1 | |
| Ammonia Solution, Strong SCHEMBL31621177 | 0.81 | MAPT (0.40) | MAPTCA2CA1FAAHMAPK1 | |
| SCHEMBL8611736 | 0.80 | MAPT (0.41) | MAPTALDH1A1FAAHCES1CES2 | |
| SCHEMBL5198247 | 0.79 | MAPT (0.31) | MAPTCA2CA1ALDH1A1 | |
| SCHEMBL28409179 | 0.76 | MAPT (0.52) | MAPTFAAHCES1CES2MEN1 | |
| SCHEMBL8490371 | 0.76 | MAPT (0.52) | MAPTFAAHCES1CES2MEN1 | |
| SCHEMBL3132066 | 0.76 | MAPT (0.39) | MAPTCA2CA1FAAHMAPK1 | |
| SCHEMBL5690760 | 0.76 | MAPT (0.52) | MAPTFAAHCES1CES2MEN1 | |
| SCHEMBL28363304 | 0.75 | THRB (0.39) | MAPTCA2CA1FAAHMAPK1 | |
| SCHEMBL23825128 | 0.74 | FDPS (0.34) | MAPTCA2CA1ALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595732-A1 | SOLVENT RESISTANT POLYAMIDE NANOFILTRATION MEMBRANES | Imperial Innovations Limited (GB) | 2013-05-29 | — | — | EP | claimed |
| WO-2012010889-A1 | SOLVENT RESISTANT POLYAMIDE NANOFILTRATION MEMBRANES | IMPERIAL INNOVATIONS LIMITED (GB) | 2012-01-26 | — | — | WO | claimed |