Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13358911 | 0.84 | ALDH1A1 (0.33) | — | |
| SCHEMBL4308557 | 0.84 | CA2 (0.36) | CA2 | |
| SCHEMBL14813153 | 0.83 | CA2 (0.36) | CA2PPARD | |
| SCHEMBL3466088 | 0.80 | PIK3CD (0.33) | CA2 | |
| SCHEMBL14813114 | 0.79 | BRAF (0.34) | — | |
| SCHEMBL13359499 | 0.76 | KMT2A (0.34) | CA2 | |
| SCHEMBL14813206 | 0.76 | POLB (0.38) | — | |
| SCHEMBL13358967 | 0.76 | HTT (0.32) | — | |
| SCHEMBL4314286 | 0.76 | CA2 (0.38) | CA2 | |
| SCHEMBL13358933 | 0.75 | HTR2A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297112-B1 | PYRAZOLE COMPOUNDS AS CCR1 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2013-04-03 | — | — | EP | disclosed |
| US-8293917-B2 | Pyrazole compounds as CCR1 antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-23 | — | — | US | disclosed |
| WO-2009137338-A1 | PYRAZOLE COMPOUNDS AS CCR1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-12 | — | — | WO | disclosed |