Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | CASP3 | P42574 | 4/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278819 | 0.91 | TDP1 (0.52) | TDP1CYP1B1CYP1A1TSHRRAB9A | |
| SCHEMBL11278840 | 0.91 | TDP1 (0.52) | TDP1CYP1B1CYP1A1TSHRRAB9A | |
| SCHEMBL24133223 | 0.91 | TDP1 (0.52) | TDP1CYP1B1CYP1A1TSHRRAB9A | |
| SCHEMBL310943 | 0.80 | CYP1B1 (1.00) | TDP1CYP1B1CYP1A1TSHRRAB9A | |
| SCHEMBL310944 | 0.80 | CYP1B1 (1.00) | TDP1CYP1B1CYP1A1TSHRRAB9A | |
| SCHEMBL3079057 | 0.80 | CYP1B1 (1.00) | TDP1CYP1B1CYP1A1TSHRRAB9A | |
| SCHEMBL11065097 | 0.80 | CYP1B1 (1.00) | TDP1CYP1B1CYP1A1TSHRRAB9A | |
| Benzene SCHEMBL28456075 | 0.80 | CYP1B1 (1.00) | TDP1CYP1B1CYP1A1TSHRRAB9A | |
| SCHEMBL8854548 | 0.79 | CRHR1 (0.48) | TDP1CYP1B1CYP1A1TSHRRAB9A | |
| SCHEMBL11597338 | 0.78 | CYP1B1 (0.95) | TDP1CYP1B1CYP1A1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012270-A2 | BONE REPLACEMENT MATERIAL DELIVERY DEVICES AND METHODS OF USE | WARSAW ORTHOPEDIC, INC. (US) | 2012-01-26 | — | — | WO | disclosed |
| US-7699917-B1 | Selectively alterable intermittent tattoo ink and system | PAGNOTTA PAT ANDREW | 2010-04-20 | — | — | US | disclosed |