SCHEMBL8854548

SCHEMBL8854548

Cc1cccc(N=NNc2ccccc2C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 5/20 0.48
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
TDP1 Q9NUW8 4/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
CASP3 P42574 2/20 0.42
SENP8 Q96LD8 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
SENP6 Q9GZR1 2/20 0.42
NSD2 O96028 1/20 0.42
HTR3E A5X5Y0 2/20 0.40
HTR3B O95264 2/20 0.40
HTR3A P46098 2/20 0.40
HTR3D Q70Z44 2/20 0.40
HTR3C Q8WXA8 2/20 0.40
CYP1A1 P04798 1/20 0.39
TSHR P16473 1/20 0.39
CYP1B1 Q16678 1/20 0.39
MAPT P10636 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11210126 0.81 MAPT (0.43) MEN1KMT2ATDP1NPC1RAB9A
SCHEMBL431706 0.79 TDP1 (0.66) CRHR1MEN1KMT2ATDP1NPC1
SCHEMBL11208479 0.78 CYP1A1 (0.48) MEN1KMT2ATDP1NPC1RAB9A
SCHEMBL24133223 0.77 TDP1 (0.52) CRHR1MEN1KMT2ATDP1NPC1
SCHEMBL11278819 0.77 TDP1 (0.52) CRHR1MEN1KMT2ATDP1NPC1
SCHEMBL11278840 0.77 TDP1 (0.52) CRHR1MEN1KMT2ATDP1NPC1
SCHEMBL29664063 0.75 MAPT (0.52) MEN1KMT2ATDP1NPC1RAB9A
SCHEMBL12523792 0.74 NPC1 (0.50) MEN1KMT2ATDP1NPC1RAB9A
SCHEMBL11981455 0.73 MEN1 (0.67) MEN1KMT2ATDP1NPC1RAB9A
SCHEMBL30102207 0.73 MEN1 (0.67) MEN1KMT2ATDP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5677380-A COATING ON IRREGULAR SURFACE MATERIAL COMPRISING ADDITION POLYMER, HEAT CURING AGENT, HALATION PREVENTIVE AGENT, HEATING TO FLUIDIZE AND CURE FILM TOSOH CORPORATION (JP) 1997-10-14 US disclosed