Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313090 | 0.99 | TSHR (0.49) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL21670764 | 0.91 | MGLL (0.44) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL1547662 | 0.85 | TSHR (0.51) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL7944138 | 0.82 | S1PR3 (0.56) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL7945499 | 0.82 | S1PR3 (0.56) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL316148 | 0.81 | TSHR (0.51) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL316706 | 0.81 | TSHR (0.51) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL28355199 | 0.80 | ALDH1A1 (0.66) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL5069966 | 0.80 | ALDH1A1 (0.66) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL9240016 | 0.80 | TSHR (0.60) | TSHRALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136001-A1 | PROTEIN KINASE MODULATING AGENTS | TUOMINEN RAIMO (FI) | 2009-11-12 | — | — | WO | disclosed |