Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HRH2 | P25021 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11774653 | 0.92 | ALDH1A1 (0.58) | ALDH1A1RECQLMAPTMEN1PTPN7 | |
| SCHEMBL11085273 | 0.91 | ALDH1A1 (0.59) | ALDH1A1RECQLMAPTMEN1PTPN7 | |
| SCHEMBL11528042 | 0.88 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1PTPN7KMT2A | |
| SCHEMBL11084203 | 0.87 | ALDH1A1 (0.56) | ALDH1A1RECQLMAPTMEN1PTPN7 | |
| SCHEMBL6046278 | 0.84 | ALDH1A1 (0.60) | ALDH1A1RECQLMAPTMEN1PTPN7 | |
| SCHEMBL22102727 | 0.83 | ALDH1A1 (0.50) | ALDH1A1RECQLMAPTMEN1PTPN7 | |
| SCHEMBL2730318 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1PTPN7KMT2A | |
| SCHEMBL21442807 | 0.81 | APP (0.49) | ALDH1A1RECQLMAPTMEN1PTPN7 | |
| Phenoxyethanol SCHEMBL15708 | 0.81 | ALDH1A1 (1.00) | ALDH1A1RECQLGAAALOX15NR1I2 | |
| Phenoxyethanol SCHEMBL167128 | 0.81 | ALDH1A1 (1.00) | ALDH1A1RECQLGAAALOX15NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827793-B2 | Core-shell compound, photosensitive resin composition including the same, photosensitive resin layer, color filter and CMOS image sensor | SAMSUNG SDI CO., LTD. (KR) | 2023-11-28 | — | — | US | disclosed |
| US-20220204775-A1 | CORE-SHELL COMPOUND, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME, PHOTOSENSITIVE RESIN LAYER, COLOR FILTER AND CMOS IMAGE SENSOR | SAMSUNG SDI CO., LTD. (KR) | 2022-06-30 | — | — | US | disclosed |
| US-7534794-B2 | Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases | BIOVITRUM AB (SE) | 2009-05-19 | — | — | US | disclosed |
| US-7071180-B2 | Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases | BIOVITRUM AB (SE) | 2006-07-04 | — | — | US | disclosed |
| EP-1178973-B1 | PYRAZINYL-PIPERAZINE- COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2005-12-21 | — | — | EP | disclosed |
| US-20040242554-A1 | CERTAIN ARYLALIPHATIC AND HETEROARYL-ALIPHATIC PIPERAZINYL PYRAZINES AND THEIR USE IN THE TREATMENT OF SEROTONIN-RELATED DISEASES | BIOVITRUM, AB, A STOCKHOLM, SWEDEN CORPORATION | 2004-12-02 | — | — | US | disclosed |
| US-20030092694-A1 | Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases | BIOVITRUM, AB, A STOCKHOLM, SWEDEN CORPORATION | 2003-05-15 | — | — | US | disclosed |
| US-6465467-B1 | DISEASES RELATED TO THE 5-HT2C RECEPTOR, ESPECIALLY EATING, MEMORY, MOOD, URINARY AND ANXIETY DISORDERS, SCHIZOPHRENIA, PAIN, SEXUAL DYSFUNCTIONS | BIOVITRUM AB (SE) | 2002-10-15 | — | — | US | disclosed |
| EP-1178973-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | Pharmacia AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000076984-A2 | NOVEL COMPOUNDS, THEIR USE AND PREPARATION | BIOVITRUM AB (SE) | 2000-12-21 | — | — | WO | disclosed |
| US-5155148-A | For stabilizing oxidizable rubbers, oils; co-polymerizable through unsaturated site | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0420790-A1 | Ester derivatives from p-hydroxydiphenylamine | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4457868-A | Method for esterification | MOBIL OIL CORPORATION (US) | 1984-07-03 | — | — | US | disclosed |
| US-4077942-A | Bis(4-anilinophenoxy) ester antioxidants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092694-A1 | Certain arylaliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases | HTR2C, HTR3C, HTR2A | ALDH1A1 763/4885RECQL 2320/4885MAPT 4036/4885 |
| US-20040242554-A1 | CERTAIN ARYLALIPHATIC AND HETEROARYL-ALIPHATIC PIPERAZINYL PYRAZINES AND THEIR USE IN THE TREATMENT OF SEROTONIN-RELATED DISEASES | HTR2C, HTR3C, HTR2A | ALDH1A1 724/4885RECQL 2293/4885MAPT 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.