⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4317405 | 0.78 | MEN1 (0.36) | — | |
| SCHEMBL780562 | 0.72 | MEN1 (0.31) | — | |
| SCHEMBL4118157 | 0.69 | — | — | |
| SCHEMBL712910 | 0.67 | TSHR (0.35) | — | |
| SCHEMBL6152272 | 0.67 | TSHR (0.35) | — | |
| SCHEMBL777726 | 0.67 | KDM4E (0.31) | — | |
| SCHEMBL4449296 | 0.67 | TSHR (0.35) | — | |
| SCHEMBL4319030 | 0.65 | TDP1 (0.39) | — | |
| SCHEMBL11802281 | 0.65 | — | — | |
| SCHEMBL5082393 | 0.65 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557153-B2 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP BV (NL) | 2009-07-07 | — | — | US | disclosed |
| EP-1951788-A1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | General Electric Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007053500-A1 | IONIZING RADIATION STABLE THERMOPLASTIC COMPOSITION, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070100059-A1 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-03 | — | — | US | disclosed |