Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4317706 | 1.00 | PDPK1 (0.47) | PDPK1CTBP2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL3917563 | 0.82 | CES1 (0.52) | CTBP2CYP2C9L3MBTL1TDP1MEN1 | |
| SCHEMBL3917561 | 0.82 | CES1 (0.52) | CTBP2CYP2C9L3MBTL1TDP1MEN1 | |
| SCHEMBL5644457 | 0.81 | SMN1; SMN2 (0.47) | CTBP2CYP2C9CYP2C19TDP1RAB9A | |
| SCHEMBL5644461 | 0.81 | SMN1; SMN2 (0.47) | CTBP2CYP2C9CYP2C19TDP1RAB9A | |
| SCHEMBL4325304 | 0.81 | SMN1; SMN2 (0.47) | CTBP2CYP2C9CYP2C19TDP1RAB9A | |
| SCHEMBL4340460 | 0.80 | HTR3E (0.56) | CTBP2MEN1KMT2ATAAR1ALDH1A1 | |
| SCHEMBL4322049 | 0.80 | HTR3E (0.56) | CTBP2MEN1KMT2ATAAR1ALDH1A1 | |
| SCHEMBL11039928 | 0.78 | CTBP2 (0.51) | PDPK1CTBP2CYP2C9L3MBTL1MAPT | |
| SCHEMBL11039934 | 0.78 | CTBP2 (0.51) | PDPK1CTBP2CYP2C9L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146696-A1 | USE OF INDOLE-3-CARBOXYLIC ESTERS FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE | Universität Tübingen (DE) | 2009-12-10 | — | — | WO | disclosed |