Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7935788 | 0.91 | ENPP1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7942022 | 0.88 | EDNRB (0.32) | — | |
| Hydrochloric Acid SCHEMBL6439096 | 0.86 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6464432 | 0.86 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL481289 | 0.86 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4063465 | 0.82 | HDAC4 (0.36) | — | |
| Hydrochloric Acid SCHEMBL6754810 | 0.81 | HDAC4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5608847 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL3808738 | 0.81 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL4315257 | 0.81 | BRD4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579416-B2 | Catalyst system for olefin polymerization | BASELL POLYOLEFINE GMBH (DE) | 2009-08-25 | — | — | US | disclosed |
| US-20070149386-A1 | Catalyst system for olefin polymerization | EQUISTAR CHEMICALS, LP | 2007-06-28 | — | — | US | disclosed |