Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL481289 | 1.00 | PDCD1 (0.31) | PDCD1CD274HTR1ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL6439096 | 1.00 | PDCD1 (0.31) | PDCD1CD274HTR1ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL7942022 | 0.90 | EDNRB (0.32) | — | |
| Hydrochloric Acid SCHEMBL7627498 | 0.90 | EDNRB (0.30) | — | |
| Hydrochloric Acid SCHEMBL4061874 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL7935788 | 0.88 | ENPP1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4318451 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL7942529 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL7938880 | 0.86 | CHRNB2 (0.33) | HTR1ADRD2HTR7CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3808738 | 0.85 | BRD4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916886-B2 | Propylene block copolymer | JAPAN POLYPROPYLENE CORPORATION (JP) | 2005-07-12 | — | — | US | disclosed |