Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.51 |
| ▸ | CNR2 | P34972 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321596 | 0.99 | AOC3 (0.50) | AOC3CNR2MAPTALDH1A1LMNA | |
| SCHEMBL4318002 | 0.87 | NTRK1 (0.47) | AOC3ALDH1A1MLNRCYP2D6 | |
| SCHEMBL4328647 | 0.83 | TAAR1 (0.40) | AOC3KIT | |
| SCHEMBL27809060 | 0.82 | AOC3 (0.60) | AOC3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4320115 | 0.82 | TAAR1 (0.41) | AOC3KIT | |
| SCHEMBL4332085 | 0.79 | CHKA (0.48) | CNR2MAPTCNR1SMN1; SMN2 | |
| SCHEMBL4333810 | 0.77 | PDE10A (0.52) | AOC3 | |
| SCHEMBL4321581 | 0.77 | CHKA (0.46) | MAPTSMN1; SMN2 | |
| SCHEMBL12601594 | 0.73 | AOC3 (0.55) | AOC3CNR2MAPTALDH1A1LMNA | |
| SCHEMBL4321578 | 0.72 | KDM4E (0.35) | MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |