Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321581 | 0.98 | CHKA (0.46) | CHKANPC1MAPTSMN1; SMN2L3MBTL3 | |
| SCHEMBL4340373 | 0.86 | MAPT (0.45) | NPC1MAPTSMN1; SMN2L3MBTL3L3MBTL1 | |
| SCHEMBL4321625 | 0.85 | SIGMAR1 (0.46) | — | |
| SCHEMBL27829430 | 0.85 | NCF1 (0.48) | CHKANPC1MAPTL3MBTL1 | |
| SCHEMBL4328642 | 0.83 | PRMT6 (0.54) | CHKAMAPTL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL9915870 | 0.81 | CHKA (0.65) | CHKANPC1MAPTSMN1; SMN2L3MBTL3 | |
| SCHEMBL27829446 | 0.79 | GFER (0.52) | MAPTSMN1; SMN2 | |
| SCHEMBL4318487 | 0.79 | AOC3 (0.51) | MAPTSMN1; SMN2CNR1CNR2 | |
| SCHEMBL4328647 | 0.78 | TAAR1 (0.40) | NPC1L3MBTL1ACHE | |
| SCHEMBL4321596 | 0.77 | AOC3 (0.50) | MAPTSMN1; SMN2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | claimed |
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |