Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 17/20 | 0.52 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332133 | 0.87 | AOC3 (0.55) | PDE10AAOC3 | |
| SCHEMBL4333812 | 0.87 | PDE10A (0.51) | PDE10AAOC3 | |
| SCHEMBL27809064 | 0.83 | AOC3 (0.43) | PDE10AAOC3 | |
| SCHEMBL4318487 | 0.77 | AOC3 (0.51) | AOC3 | |
| SCHEMBL4321596 | 0.76 | AOC3 (0.50) | AOC3 | |
| SCHEMBL27809009 | 0.75 | KCNH2 (0.37) | — | |
| SCHEMBL10496803 | 0.75 | PDE10A (0.53) | PDE10ATRPV3AOC3 | |
| SCHEMBL4332085 | 0.75 | CHKA (0.48) | — | |
| SCHEMBL16516277 | 0.74 | PDE10A (0.58) | PDE10ATRPV3 | |
| SCHEMBL8085680 | 0.74 | PDE10A (0.58) | PDE10ATRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | claimed |
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |