Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TYMP | P19971 | 3/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCR10 | P46092 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17831274 | 0.85 | LMNA (0.56) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL3914305 | 0.85 | LMNA (0.62) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL4398512 | 0.84 | CA12 (0.56) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL15325016 | 0.83 | LMNA (0.61) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL11879496 | 0.83 | LMNA (0.61) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL13897245 | 0.82 | LMNA (0.63) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL5312329 | 0.81 | LMNA (0.70) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL13657445 | 0.80 | LMNA (0.57) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL3835016 | 0.80 | LMNA (0.60) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| Potassium Ion SCHEMBL5317511 | 0.80 | LMNA (0.68) | LMNATHRBCYP2C19CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160289197-A1 | PRODUCTION METHOD FOR PRODUCING N-BENZYL-2-(2-NITRO-1H-IMIDAZOL-1-YL) ACETAMIDE | MINISTERIO DE EDUCACIÓN (SV) | 2016-10-06 | — | — | US | claimed |
| WO-2011145957-A1 | AGENTS AND METHODS FOR DETECTION AND/OR IMAGING OF HYPOXIA | AUCKLAND UNISERVICES LIMITED (NZ) | 2011-11-24 | — | — | WO | disclosed |
| EP-1202973-B1 | PREPARATION OF COMPOUNDS USEFUL FOR THE DETECTION OF HYPOXIA | UNIV PENNSYLVANIA (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008099165-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2008-08-21 | — | — | WO | disclosed |
| US-7230115-B1 | Preparation of compounds useful for the detection of hypoxia | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-06-12 | — | — | US | disclosed |
| EP-0669913-B1 | DETECTION OF HYPOXIA | UNIV PENNSYLVANIA (US) | 2003-03-05 | — | — | EP | disclosed |
| US-5843404-A | Immunogenic conjugates of nitroaromatic compounds and proteins; monoclonal antibodies specific for nitroaromatic compounds , their protein conjugates | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0669913-A4 | DETECTION OF HYPOXIA. | UNIV PENNSYLVANIA (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5540908-A | DETECTION OF OXYGEN DEPRIVATION USING IMMUNOHISTOLOGICAL METHODS | THE TRUSTEES OF THE UNIV. OF PENNSYLVANIA (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0669913-A1 | DETECTION OF HYPOXIA | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994011348-A1 | DETECTION OF HYPOXIA | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1994-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289197-A1 | PRODUCTION METHOD FOR PRODUCING N-BENZYL-2-(2-NITRO-1H-IMIDAZOL-1-YL) ACETAMIDE | NAAA, NIT2, NAA15 | LMNA 2287/4885THRB 1557/4885CYP2C19 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.