Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 11/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482959 | 0.88 | EPHX2 (0.59) | EPHX2HSD11B1TRPV1GAADPP4 | |
| SCHEMBL14973800 | 0.81 | EPHX2 (0.59) | EPHX2HSD11B1TRPV1GAAMAPT | |
| SCHEMBL13783793 | 0.80 | TRPV1 (0.52) | EPHX2HSD11B1TRPV1GAADPP4 | |
| SCHEMBL3818669 | 0.79 | EPHX2 (0.57) | EPHX2HSD11B1TRPV1GAADPP4 | |
| SCHEMBL3818667 | 0.79 | EPHX2 (0.57) | EPHX2HSD11B1TRPV1GAADPP4 | |
| SCHEMBL25154314 | 0.79 | EPHX2 (0.56) | EPHX2HSD11B1TRPV1GAARBP4 | |
| SCHEMBL25154349 | 0.79 | EPHX2 (0.56) | EPHX2HSD11B1TRPV1GAARBP4 | |
| SCHEMBL1349136 | 0.79 | EPHX2 (0.64) | EPHX2HSD11B1TRPV1GAADPP4 | |
| SCHEMBL4635199 | 0.76 | HSD11B1 (0.46) | HSD11B1TRPV1DPP4 | |
| SCHEMBL4778176 | 0.76 | MALT1 (0.34) | HSD11B1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |