Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635199 | 0.80 | HSD11B1 (0.46) | MALT1PTPN11TRPV1HSD11B1 | |
| SCHEMBL4880417 | 0.79 | PDE10A (0.39) | MALT1TRPV1 | |
| SCHEMBL4320157 | 0.76 | EPHX2 (0.56) | TRPV1HSD11B1 | |
| SCHEMBL4635503 | 0.76 | KDM4E (0.54) | HSD11B1 | |
| SCHEMBL4880388 | 0.75 | ALDH1A1 (0.44) | MALT1 | |
| SCHEMBL4880724 | 0.74 | KDM4E (0.44) | MALT1TRPV1 | |
| SCHEMBL4635540 | 0.74 | CYP1A2 (0.62) | HSD11B1 | |
| SCHEMBL27703385 | 0.73 | CYP1A2 (0.49) | MALT1TRPV1 | |
| SCHEMBL20406252 | 0.73 | CYP1A2 (0.53) | TRPV1 | |
| SCHEMBL16496334 | 0.72 | DPP4 (0.43) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |