Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4320489 | 0.79 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL4319487 | 0.73 | TRPV1 (0.53) | GAACYP1A2SMN1; SMN2TRPV1MAPT | |
| SCHEMBL4319481 | 0.73 | TRPV1 (0.53) | GAACYP1A2SMN1; SMN2TRPV1MAPT | |
| SCHEMBL30354938 | 0.69 | MAPT (0.55) | GAACYP1A2SMN1; SMN2MAPTMEN1 | |
| SCHEMBL29151334 | 0.69 | MAPT (0.55) | GAACYP1A2SMN1; SMN2MAPTMEN1 | |
| SCHEMBL6814707 | 0.68 | CYP1A2 (0.66) | GAACYP1A2SMN1; SMN2MAPTMEN1 | |
| SCHEMBL10421628 | 0.66 | CYP1A2 (0.62) | GAACYP1A2SMN1; SMN2MAPTMEN1 | |
| SCHEMBL477396 | 0.65 | CYP1A2 (0.73) | GAACYP1A2SMN1; SMN2MAPTMEN1 | |
| SCHEMBL477394 | 0.65 | CYP1A2 (0.73) | GAACYP1A2SMN1; SMN2MAPTMEN1 | |
| SCHEMBL30354788 | 0.65 | GAA (0.64) | GAACYP1A2SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |