Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 14/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4320186 | 0.79 | GAA (0.42) | TRPV1 | |
| SCHEMBL2723660 | 0.69 | TRPV1 (0.79) | TRPV1 | |
| SCHEMBL4327380 | 0.67 | TRPV1 (0.73) | TRPV1 | |
| SCHEMBL4327376 | 0.67 | TRPV1 (0.73) | TRPV1 | |
| SCHEMBL4012359 | 0.66 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL20379672 | 0.65 | NPC1 (0.72) | NAMPT | |
| SCHEMBL15467437 | 0.64 | TRPM8 (0.46) | TRPV1P2RY1NAMPT | |
| SCHEMBL28729179 | 0.64 | EPHX2 (1.00) | NAMPT | |
| SCHEMBL11003408 | 0.64 | EPHX2 (1.00) | NAMPT | |
| SCHEMBL17542180 | 0.63 | EPHX2 (0.59) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |