Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4319487 | 1.00 | TRPV1 (0.53) | TRPV1HSD11B1GAACYP1A2SMN1; SMN2 | |
| SCHEMBL4319338 | 0.78 | TRPV1 (0.48) | TRPV1HSD11B1GAA | |
| SCHEMBL4327380 | 0.77 | TRPV1 (0.73) | TRPV1 | |
| SCHEMBL4327376 | 0.77 | TRPV1 (0.73) | TRPV1 | |
| SCHEMBL4321219 | 0.75 | ALDH1A1 (0.46) | GAACYP1A2SMN1; SMN2MEN1MAPT | |
| SCHEMBL4321217 | 0.75 | ALDH1A1 (0.46) | GAACYP1A2SMN1; SMN2MEN1MAPT | |
| SCHEMBL13783793 | 0.75 | TRPV1 (0.52) | TRPV1HSD11B1GAA | |
| SCHEMBL4320186 | 0.73 | GAA (0.42) | TRPV1GAACYP1A2SMN1; SMN2MEN1 | |
| SCHEMBL4461101 | 0.72 | TSHR (0.47) | TRPV1HSD11B1GAAMAPT | |
| SCHEMBL4461106 | 0.72 | TSHR (0.47) | TRPV1HSD11B1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | claimed |