⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4320663 | 1.00 | — | — | |
| SCHEMBL4320669 | 1.00 | — | — | |
| Succinic Acid SCHEMBL8707346 | 0.82 | LMNA (0.56) | — | |
| SCHEMBL16426620 | 0.82 | TSHR (0.57) | — | |
| SCHEMBL17029478 | 0.82 | TSHR (0.57) | — | |
| SCHEMBL16426623 | 0.82 | TSHR (0.57) | — | |
| SCHEMBL24601557 | 0.80 | — | — | |
| SCHEMBL14540222 | 0.78 | — | — | |
| Succinic Acid SCHEMBL28787941 | 0.76 | LMNA (0.65) | — | |
| Succinic Acid SCHEMBL15051622 | 0.76 | LMNA (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200278346-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ADJACENT ACQUISITION CO., LLC | 2020-09-03 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| WO-2018204764-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION (US) | 2018-11-08 | — | — | WO | disclosed |
| US-20180051001-A1 | Tetrahydrothiophene-based GABA Aminotransferase Inactivators | NORTHWESTERN UNIVERSITY (US) | 2018-02-22 | — | — | US | disclosed |
| US-9856231-B2 | Tetrahydrothiophene-based GABA aminotransferase inactivators | NORTHWESTERN UNIVERSITY (US) | 2018-01-02 | — | — | US | disclosed |
| US-20160264544-A1 | Tetrahydrothiophene-based GABA Aminotransferase Inactivators | NORTHWESTERN UNIVERSITY | 2016-09-15 | — | — | US | disclosed |
| US-20160264544-A1 | Tetrahydrothiophene-based GABA Aminotransferase Inactivators | NORTHWESTERN UNIVERSITY | 2016-09-15 | — | — | US | disclosed |
| US-20150309021-A1 | Advanced Drug Development and Manufacturing | LOS ALAMOS NATIONAL SECURITY, LLC | 2015-10-29 | — | — | US | disclosed |
| EP-2511844-B1 | X-ray microscope | XRPRO SCIENCES INC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2511844-A2 | Advanced drug development and manufacturing | Los Alamos National Security, LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| EP-2084519-B1 | X-RAY FLUORESCENCE ANALYSIS METHOD | LOS ALAMOS NAT SECURITY LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2084519-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | Los Alamos National Security, LLC (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008127291-A2 | ADVANCED DRUG DEVELOPMENT AND MANUFACTURING | LOS ALAMOS NATIONAL SECURITY, LLC (US) | 2008-10-23 | — | — | WO | disclosed |
| US-20080220441-A1 | Advanced drug development and manufacturing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-11 | — | — | US | disclosed |
| US-7381748-B1 | Compounds and related methods for inhibition of gamma-aminobutyric acid aminotransferase | NORTHWESTERN UNIVERSITY (US) | 2008-06-03 | — | — | US | disclosed |