Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.56 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.56 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.56 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KDM5C | P41229 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4320669 | 0.82 | — | — | |
| SCHEMBL4320657 | 0.82 | — | — | |
| SCHEMBL4320663 | 0.82 | — | — | |
| Propionic Acid SCHEMBL29203842 | 0.81 | FFAR3 (0.62) | LMNAHDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL29244070 | 0.81 | FFAR3 (0.62) | LMNAHDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL15051622 | 0.80 | LMNA (0.65) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL28787942 | 0.80 | LMNA (0.65) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL28844915 | 0.80 | EGLN1 (0.64) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL28787941 | 0.80 | LMNA (0.65) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Succinic Acid SCHEMBL5874481 | 0.79 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180457-A1 | METHOD FOR REDUCING THE OPTICAL REFLECTIVITY OF A COPPER AND COPPER ALLOY CIRCUITRY AND TOUCH SCREEN DEVICE | ATOTECH Deutschland GmbH (DE) | 2017-06-21 | — | — | EP | disclosed |
| EP-3049549-A1 | METHOD FOR TREATMENT OF RECESSED STRUCTURES IN DIELECTRIC MATERIALS FOR SMEAR REMOVAL | ATOTECH Deutschland GmbH (DE) | 2016-08-03 | — | — | EP | disclosed |
| WO-2016023828-A1 | METHOD FOR REDUCING THE OPTICAL REFLECTIVITY OF A COPPER AND COPPER ALLOY CIRCUITRY AND TOUCH SCREEN DEVICE | ATOTECH DEUTSCHLAND GMBH (DE) | 2016-02-18 | — | — | WO | disclosed |
| WO-2014154689-A1 | ELECTROLESS COPPER PLATING SOLUTION | ATOTECH DEUTSCHLAND GMBH (DE) | 2014-10-02 | — | — | WO | disclosed |
| EP-2764135-A2 | FORMALDEHYDE-FREE ELECTROLESS COPPER PLATING SOLUTION | Atotech Deutschland GmbH (DE) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050332-A2 | FORMALDEHYDE-FREE ELECTROLESS COPPER PLATING SOLUTION | ATOTECH DEUTSCHLAND GMBH (DE) | 2013-04-11 | — | — | WO | disclosed |
| EP-0850293-A1 | SUCCINIC ACID DERIVATIVE DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997008288-A1 | SUCCINIC ACID DERIVATIVE DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1997-03-06 | — | — | WO | disclosed |