Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23602095 | 0.80 | CYP3A4 (0.46) | BACE1TDP1MEN1CYP3A4KMT2A | |
| SCHEMBL30279766 | 0.80 | CYP3A4 (0.46) | BACE1TDP1MEN1CYP3A4KMT2A | |
| SCHEMBL4691914 | 0.80 | TAAR1 (0.39) | BACE1NQO1TDP1MEN1CYP3A4 | |
| SCHEMBL31167142 | 0.80 | TAAR1 (0.39) | BACE1NQO1TDP1MEN1CYP3A4 | |
| SCHEMBL7520723 | 0.79 | CYP3A4 (0.47) | TDP1CYP3A4HPGDPTPN1CA1 | |
| SCHEMBL515826 | 0.74 | PTPN1 (0.52) | BACE1TDP1CYP3A4HPGDPTPN1 | |
| SCHEMBL8763536 | 0.74 | CA1 (0.50) | TDP1MEN1CYP3A4KMT2AHPGD | |
| SCHEMBL23628384 | 0.74 | PTPN1 (0.44) | MEN1CYP3A4KMT2AHPGDPTPN1 | |
| SCHEMBL21583494 | 0.73 | HSD17B10 (0.50) | TDP1MEN1CYP3A4KMT2AHPGD | |
| SCHEMBL28794852 | 0.73 | SELL (0.58) | TDP1MEN1CYP3A4KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121965-A | Insect pheromone-containing biodegradable agricultural film and preparation method thereof | 陕西科技大学 | 2021-07-16 | — | — | CN | claimed |
| CN-109293493-B | Novel benzhydryl compounds with mycobacterium tuberculosis inhibiting activity | 清华大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-113121965-A | Insect pheromone-containing biodegradable agricultural film and preparation method thereof | 陕西科技大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-109293493-A | With the inhibition active novel benzhydryl class compound of mycobacterium tuberculosis | 清华大学 | 2019-02-01 | — | — | CN | disclosed |
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | UNIVERSITY OF MISSISSIPPI | 2009-07-30 | — | — | US | disclosed |
| US-7468445-B2 | Antigiardial agents and use thereof | UNIVERSITY OF MISSISSIPPI (US) | 2008-12-23 | — | — | US | disclosed |
| US-20060106091-A1 | Antigiardial agents and use thereof | THE UNIVERSITY OF MISSISSIPPI | 2006-05-18 | — | — | US | disclosed |
| WO-2004014886-A1 | ANTIGIARDIAL AGENTS AND USE THEREOF | UNIVERSITY OF MISSISSIPPI (US) | 2004-02-19 | — | — | WO | disclosed |
| US-5859067-A | PREPARING BIS(2-HYDROXY-1-NAPHTHYL)DECANE FROM THE CORRESPONDING DIACID; FORMING ACID DICHLORIDE; TREATING WITH 2-NAPHTHOL; REARRANGEMENT; REDUCTION; INHIBITS ACTION OF ADENOSINE TRIPHOSPHATASE | ROUFOGALIS BASIL DON (AU) | 1999-01-12 | — | — | US | disclosed |
| US-5741821-A | PHENOLIC ENZYME INHIBITORS | THE UNIVERSITY OF SYDNEY (AU) | 1998-04-21 | — | — | US | disclosed |
| EP-0703780-A4 | USE OF NATURAL PRODUCTS AND RELATED SYNTHETIC COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE | UNIV SYDNEY (AU) | 1998-01-07 | — | — | EP | disclosed |
| EP-0703780-A1 | USE OF NATURAL PRODUCTS AND RELATED SYNTHETIC COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE | THE UNIVERSITY OF SYDNEY (AU) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994028886-A1 | USE OF NATURAL PRODUCTS AND RELATED SYNTHETIC COMPOUNDS FOR THE TREATMENT OF CARDIOVASCULAR DISEASE | THE UNIVERSITY OF SYDNEY (AU) | 1994-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106091-A1 | Antigiardial agents and use thereof | GPER1, ENPP2, ALPI | BACE1 3168/4885NQO1 2161/4885TDP1 4344/4885 |
| US-20090192152-A1 | Novel Antigiardial Agents and Methods of Use Thereof | ENPP2, GPER1, ALPI | BACE1 3152/4885NQO1 2624/4885TDP1 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.