SCHEMBL4321964

SCHEMBL4321964

N#CCC#N.O=C(O)C1=CC=C2C(=Cc3ccccc32)C1=O

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.33
▸ MAOA P21397 1/20 0.33
▸ MAOB P27338 1/20 0.33
▸ TTR P02766 1/20 0.32
▸ PTPRC P08575 2/20 0.31
▸ CDC25A P30304 1/20 0.31
▸ CDC25B P30305 1/20 0.31
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL604996 0.89 MAOA (0.39) KMT2AMAOAMAOBTTRPTPRC
SCHEMBL31536344 0.76 CDC25A (0.35) KMT2ACDC25ACDC25B
SCHEMBL8014888 0.76 CDC25A (0.40) KMT2AMAOATTRCDC25ACDC25B
SCHEMBL28472055 0.76 CDC25A (0.33) KMT2ACDC25ACDC25B
Anthraquinone SCHEMBL8529111 0.73 CDC25B (0.41) KMT2AMAOAMAOBTTRCDC25A
SCHEMBL599579 0.72 TTR (0.44) KMT2ATTRPTPRCCDC25ACDC25B
SCHEMBL600297 0.72 TTR (0.44) KMT2ATTRPTPRCCDC25ACDC25B
SCHEMBL10943592 0.71 CDC25A (0.36) CDC25ACDC25B
SCHEMBL9265088 0.71 GPR84 (0.39) KMT2AMAOAPTPRCCDC25ACDC25B
SCHEMBL10945776 0.71 CDC25A (0.34) CDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105425555-B Electron transport material, Electrophtography photosensor, handle box and imaging device 富士施乐株式会社 2019-12-03 — — CN disclosed
CN-105425555-A Electron transport material, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO LTD 2016-03-23 — — CN disclosed
US-7491989-B2 Positive charging photoreceptor XEROX CORPORATION (US) 2009-02-17 — — US disclosed
EP-1640808-B1 Photoconductive imaging members XEROX CORP (US) 2008-07-09 — — EP disclosed
US-7390601-B2 Imaging member comprising modified binder XEROX CORPORATION (US) 2008-06-24 — — US disclosed
US-7312007-B2 Hole blocking layer containing a metal oxide (TiO2) having an aspect ratio of 4-5 and powder resistance of 1x104-6x104 ohm/cm when applied at a pressure of 650-50 kg/cm2 and a binder; photogenerating layer; and a charge transport layer XEROX CORPORATION (US) 2007-12-25 — — US disclosed
US-20070023747-A1 Positive charging photoreceptor XEROX CORPORATION (US) 2007-02-01 — — US disclosed
US-20060286470-A1 Imaging member XEROX CORPORATION 2006-12-21 — — US disclosed
US-7070894-B2 Photoconductive imaging members XEROX CORPORATION (US) 2006-07-04 — — US disclosed
US-7070892-B2 Imaging members XEROX CORPORATION (US) 2006-07-04 — — US disclosed
EP-1640808-A2 Photoconductive imaging members Xerox Corporation (US) 2006-03-29 — — EP disclosed
US-20060057480-A1 Photoconductive imaging members XEROX CORPORATION 2006-03-16 — — US disclosed
US-6946226-B2 Photoconductive imaging members XEROX CORPORATION (US) 2005-09-20 — — US disclosed
US-20050175913-A1 Photoconductive imaging members XEROX CORPORATION 2005-08-11 — — US disclosed
US-20050164106-A1 Imaging members XEROX CORPORATION 2005-07-28 — — US disclosed
US-20050042533-A1 Photoconductive imaging members XEROX CORPORATION 2005-02-24 — — US disclosed
US-6858363-B2 Photoconductive imaging members XEROX CORPORATION (US) 2005-02-22 — — US disclosed
US-20040197686-A1 Prevents, or minimizes dark injection, and wherein the resulting photoconducting members possess, for example, excellent photoinduced discharge characteristics, cyclic and environmental stability and acceptable charge deficient spot XEROX CORPORATION 2004-10-07 — — US disclosed
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