Ethylene Glycol

Ethylene Glycol

SCHEMBL4322286

COC.OCCO.c1ccc2c(c1)-c1ccccc1-2

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 5/20 0.40
CDC25A P30304 4/20 0.40
CDC25B P30305 4/20 0.40
MAPT P10636 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
LMNA P02545 3/20 0.40
RAB9A P51151 3/20 0.40
BLM P54132 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
HPGD P15428 3/20 0.40
MAP2K7 O14733 2/20 0.40
GMNN O75496 2/20 0.40
TP53 P04637 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
THPO P40225 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL4334499 0.87 MEN1 (0.45) ALDH1A1KDM4ECDC25ACDC25BMAPT
Ether SCHEMBL4325341 0.81 ALDH1A1 (0.42) ALDH1A1KDM4ECDC25ACDC25BTDP1
2-Methoxyethanol SCHEMBL4330534 0.81 ALDH1A1 (0.44) ALDH1A1KDM4ECDC25ACDC25BMAPT
Biphenyl SCHEMBL1495102 0.80 ALDH1A1 (0.50) ALDH1A1MAPTTDP1RAB9ASMN1; SMN2
O-Xylene SCHEMBL7784479 0.80 ACHE (0.56) ALDH1A1KDM4EMAPTTDP1SMN1; SMN2
Benzene SCHEMBL28209026 0.77 TSHR (0.42) ALDH1A1TDP1RECQLTSHRCA4
Ethylene Glycol SCHEMBL23466901 0.74 TSHR (0.47) ALDH1A1KDM4ECDC25ACDC25BRAB9A
Methyl Alcohol SCHEMBL27954456 0.73 KMT2A (0.50) ALDH1A1KDM4ECDC25ACDC25BMAPT
P-Xylene SCHEMBL235089 0.73 ACHE (0.50) ALDH1A1TDP1LMNASMN1; SMN2CA1
Ethylene Glycol SCHEMBL15995529 0.73 TSHR (0.56) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101326213-B Epoxy resin composition for sealing and electronic component device HITACHI CHEMICAL CO LTD 2011-04-20 CN disclosed
US-20090062430-A1 Epoxy Resin Composition for Sealing and Electronic Component Device HITACHI CHEMICAL CO., LTD. (JP) 2009-03-05 US disclosed
CN-101326213-A Epoxy resin composition for sealing and electronic component device HITACHI CHEMICAL CO LTD (JP) 2008-12-17 CN disclosed