Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4323062 | 0.79 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3HTR1AGRIN2B | |
| SCHEMBL18034964 | 0.70 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3GRIN2BGRIN1 | |
| SCHEMBL11638679 | 0.70 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4457606 | 0.69 | SLC6A4 (0.81) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4463258 | 0.68 | SLC6A4 (0.79) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4333714 | 0.68 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3GRIN2BGRIN1 | |
| SCHEMBL12363815 | 0.67 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL29843344 | 0.67 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL1120086 | 0.66 | SLC6A4 (0.77) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL12633242 | 0.66 | SLC6A4 (0.77) | SLC6A4SLC6A2SLC6A3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |