Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.60 |
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454609 | 0.82 | SLC6A2 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4455973 | 0.81 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4458425 | 0.77 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL4476207 | 0.76 | SLC6A2 (0.47) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18034964 | 0.76 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3DRD1DRD5 | |
| SCHEMBL11638679 | 0.76 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3HRH3 | |
| SCHEMBL29843344 | 0.73 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3DRD1DRD5 | |
| SCHEMBL12363815 | 0.73 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3DRD1DRD5 | |
| SCHEMBL3088673 | 0.70 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3DRD1DRD5 | |
| SCHEMBL4470550 | 0.70 | KDM4E (0.41) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |