Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 12/20 | 0.66 |
| ▸ | RET | P07949 | 1/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.66 |
| ▸ | KIT | P10721 | 1/20 | 0.66 |
| ▸ | SRC | P12931 | 1/20 | 0.66 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.66 |
| ▸ | FLT1 | P17948 | 1/20 | 0.66 |
| ▸ | FLT4 | P35916 | 1/20 | 0.66 |
| ▸ | KDR | P35968 | 1/20 | 0.66 |
| ▸ | FRK | P42685 | 1/20 | 0.66 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.66 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4324513 | 0.92 | CSF1R (0.66) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL13340328 | 0.90 | CSF1R (0.65) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL4317671 | 0.88 | CSF1R (0.53) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL4314547 | 0.88 | SIRT2 (0.51) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL4314543 | 0.87 | BRAF (0.52) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL27167178 | 0.87 | CSF1R (0.67) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL4318196 | 0.86 | CSF1R (0.66) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL13340335 | 0.82 | CSF1R (0.65) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL2064858 | 0.81 | CSF1R (0.67) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL3474628 | 0.79 | CSF1R (1.00) | CSF1RRETPDGFRBKITSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099774-A1 | INHIBITORS OF KINASE ACTIVITY | Cytopia Research Pty Ltd (AU) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008058341-A1 | INHIBITORS OF KINASE ACTIVITY | CYTOPIA RESEARCH PTY LTD (AU) | 2008-05-22 | — | — | WO | disclosed |