SCHEMBL432443

SCHEMBL432443

O=C(O)C(S)C(C(S)C(=O)O)(C(S)C(=O)O)C(CO)(CO)CO

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RNPEP Q9H4A4 1/20 0.37
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
ABCB11 O95342 1/20 0.36
F2 P00734 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
KMT2A Q03164 1/20 0.36
DUSP3 P51452 1/20 0.36
PTPN5 P54829 1/20 0.36
PTPN11 Q06124 1/20 0.36
LMNA P02545 1/20 0.36
CYP2C9 P11712 1/20 0.36
HIF1A Q16665 1/20 0.36
FOLH1 Q04609 1/20 0.32
OR51E2 Q9H255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10351699 0.76 ALDH1A1 (0.31) ALDH1A1HIF1A
SCHEMBL29092215 0.76 RNPEP (0.39) RNPEPHPGDHSD17B10TDP1ABCB11
SCHEMBL433624 0.73 SLC22A6 (0.35) TDP1LMNA
SCHEMBL300184 0.71
SCHEMBL9763414 0.70 RNPEP (0.34) RNPEPHPGDHSD17B10TDP1ABCB11
SCHEMBL17363654 0.70 RNPEP (0.39) RNPEPHPGDHSD17B10TDP1ABCB11
SCHEMBL1276307 0.69 PTGS1 (0.36) RNPEPHPGDHSD17B10TDP1ABCB11
SCHEMBL1132707 0.67 ALDH1A1 (0.37) RNPEPHPGDHSD17B10TDP1ABCB11
SCHEMBL2770550 0.67 TDP1 (0.40) RNPEPHPGDHSD17B10TDP1ABCB11
SCHEMBL8997938 0.65 RNPEP (0.50) RNPEPHPGDHSD17B10TDP1ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129353-B1 METHOD FOR MANUFACTURING XYLYLENE DIISOCYANATES IN THE GASEOUS PHASE COVESTRO DEUTSCHLAND AG (DE) 2024-02-28 EP claimed
EP-3696216-A1 FOAMABLE, SEAL-LAYER FORMING MULTICOMPONENT COMPOSITION AND ITS USE Hilti Aktiengesellschaft (LI) 2020-08-19 EP claimed
EP-3158012-B1 FIRE-RESISTANT COMPOUND AND ITS UTILISATION HILTI AG (LI) 2020-02-19 EP claimed
US-10392516-B2 Fire protection composition and use thereof HILTI AKTIENGESELLSCHAFT (LI) 2019-08-27 US claimed
US-10287504-B2 Composition that forms an insulating layer and use thereof HILTI AKTIENGESELLSCHAFT (LI) 2019-05-14 US claimed
EP-2963457-B1 OPTICAL MATERIAL, COMPOSITION FOR USE THEREIN, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2018-07-11 EP claimed
EP-3129352-B1 METHOD FOR MANUFACTURING XYLYLENE DIISOCYANATES IN THE GASEOUS PHASE COVESTRO DEUTSCHLAND AG (DE) 2017-11-15 EP claimed
EP-2921511-B1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL AND MANUFACTURING METHOD FOR SAME MITSUI CHEMICALS INC (JP) 2017-11-01 EP claimed
EP-2935475-B1 INSULATING LAYER-FORMING COMPOSITION AND USE THEREOF HILTI AG (LI) 2017-07-19 EP claimed
US-20170145223-A1 Fireproof Composition and Use Thereof HILTI AKTIENGESELLSCHAFT (LI) 2017-05-25 US claimed
US-20170130066-A1 Fire Protection Composition and Use Thereof HILTI AKTIENGESELLSCHAFT (LI) 2017-05-11 US claimed
US-20170130068-A1 Fireprotection Composition and Use Thereof HILTI AKTIENGESELLSCHAFT (LI) 2017-05-11 US claimed
EP-2957606-A1 Fire-resistant compound and its utilisation HILTI Aktiengesellschaft (LI) 2015-12-23 EP claimed
EP-2957605-A1 Fire-resistant compound and its utilisation HILTI Aktiengesellschaft (LI) 2015-12-23 EP claimed
EP-2957604-A1 Fire-resistant compound and its utilisation HILTI Aktiengesellschaft (LI) 2015-12-23 EP claimed
US-20150337160-A1 INSULATING LAYER-FORMING COMPOSITION AND THE USE THEREOF HILTI AKTIENGESELLSCHAFT (LI) 2015-11-26 US claimed
US-20150299578-A1 COMPOSITION THAT FORMS AN INSULATING LAYER AND USE THEREOF HILTI AKTIENGESELLSCHAFT (LI) 2015-10-22 US claimed
EP-0645647-B2 Process for the reproduction of polyurethane lens HOYA CORP (JP) 2006-10-04 EP claimed
EP-0802431-B1 Process for the production of polyurethane lens HOYA CORP (JP) 2002-01-16 EP claimed
EP-0803743-B1 Process for the production of polyurethane lens HOYA CORP (JP) 2002-01-16 EP claimed