Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 12/20 | 1.00 |
| ▸ | SSTR3 | P32745 | 13/20 | 0.67 |
| ▸ | SSTR5 | P35346 | 9/20 | 0.67 |
| ▸ | SSTR4 | P31391 | 6/20 | 0.67 |
| ▸ | SSTR2 | P30874 | 6/20 | 0.66 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR1E | P28566 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430387 | 0.78 | SSTR1 (0.63) | SSTR1SSTR3SSTR5SSTR4ADRB1 | |
| SCHEMBL1928394 | 0.78 | SSTR1 (0.63) | SSTR1SSTR3SSTR5SSTR4ADRB1 | |
| SCHEMBL4244351 | 0.78 | SSTR1 (0.63) | SSTR1SSTR3SSTR5SSTR4ADRB1 | |
| SCHEMBL27577264 | 0.77 | SSTR1 (0.63) | SSTR1SSTR3SSTR5SSTR4SSTR2 | |
| SCHEMBL1927159 | 0.77 | SSTR1 (0.63) | SSTR1SSTR3SSTR5SSTR4SSTR2 | |
| Hydrochloric Acid SCHEMBL6723717 | 0.77 | SSTR1 (0.62) | SSTR1SSTR3SSTR5SSTR4ADRB1 | |
| Hydrochloric Acid SCHEMBL27472186 | 0.77 | SSTR1 (0.62) | SSTR1SSTR3SSTR5SSTR4ADRB1 | |
| SCHEMBL1929179 | 0.76 | SSTR1 (0.61) | SSTR1SSTR3SSTR5SSTR4SSTR2 | |
| SCHEMBL1929174 | 0.76 | SSTR1 (0.61) | SSTR1SSTR3SSTR5SSTR4SSTR2 | |
| SCHEMBL1929176 | 0.76 | SSTR1 (0.61) | SSTR1SSTR3SSTR5SSTR4SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638546-B1 | Imidazolyl derivatives | IPSEN PHARMA S.A.S. (FR) | 2009-12-29 | — | — | US | claimed |