Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | TACR3 | P29371 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138474 | 0.83 | TSHR (0.46) | SMN1; SMN2TSHRKMT2AALDH1A1ESR1 | |
| SCHEMBL2857927 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRKMT2AGAA | |
| SCHEMBL18217967 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRKMT2AALDH1A1KDM4E | |
| SCHEMBL4022364 | 0.78 | SMN1; SMN2 (0.33) | SMN1; SMN2TSHRKMT2AALDH1A1ESR1 | |
| SCHEMBL13110328 | 0.76 | TSHR (0.56) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL4018833 | 0.76 | S1PR4 (0.33) | SMN1; SMN2TSHRKMT2A | |
| SCHEMBL1138561 | 0.76 | TSHR (0.44) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL4325797 | 0.76 | TSHR (0.38) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL1232474 | 0.75 | SMN1; SMN2 (0.36) | SMN1; SMN2TSHRKMT2AGAATACR1 | |
| SCHEMBL4982955 | 0.74 | ALDH1A1 (0.36) | SMN1; SMN2TSHRKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732168-B2 | Method of preparing ethylene polymers by controlled high pressure polymerization | BASF SE (DE) | 2017-08-15 | — | — | US | disclosed |
| US-9732168-B2 | Method of preparing ethylene polymers by controlled high pressure polymerization | BASF SE (DE) | 2017-08-15 | — | — | US | disclosed |
| US-20130150542-A1 | Method Of Preparing Ethylene Polymers By Controlled High Pressure Polymerization | BASF SE (DE) | 2013-06-13 | — | — | US | disclosed |
| US-20130150542-A1 | Method Of Preparing Ethylene Polymers By Controlled High Pressure Polymerization | BASF SE (DE) | 2013-06-13 | — | — | US | disclosed |
| US-8168725-B2 | Degradation of polypropylene with hydroxylamine ester compositions | BASF SE (DE) | 2012-05-01 | — | — | US | disclosed |
| US-8168725-B2 | Degradation of polypropylene with hydroxylamine ester compositions | BASF SE (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20110207892-A1 | DEGRADATION OF POLYPROPYLENE WITH HYDROXYLAMINE ESTER COMPOSITIONS | ROTH MICHAEL | 2011-08-25 | — | — | US | disclosed |
| US-20110207892-A1 | DEGRADATION OF POLYPROPYLENE WITH HYDROXYLAMINE ESTER COMPOSITIONS | ROTH MICHAEL | 2011-08-25 | — | — | US | disclosed |
| US-7956109-B2 | Degradation of polypropylene with hydroxylamine ester compositions | BASF SE (DE) | 2011-06-07 | — | — | US | disclosed |
| US-7956109-B2 | Degradation of polypropylene with hydroxylamine ester compositions | BASF SE (DE) | 2011-06-07 | — | — | US | disclosed |
| EP-1404729-B1 | METHOD OF GRAFTING ETHYLENICALLY UNSATURATED CARBOXYLIC ACID DERIVATIVES ONTO THERMOPLASTIC POLYMERS USING HYDROXYLAMINE ESTERS | CIBA SC HOLDING AG (CH) | 2007-11-21 | — | — | EP | disclosed |
| US-7230042-B2 | Flame retardant polymer compositions containing hydroxylamine esters | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-06-12 | — | — | US | disclosed |
| US-7230042-B2 | Flame retardant polymer compositions containing hydroxylamine esters | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-06-12 | — | — | US | disclosed |
| US-20060128903-A1 | Process for the controlled increase in the molecular weight of polyethylenes | ROTH MICHAEL | 2006-06-15 | — | — | US | disclosed |
| EP-1282630-B1 | Process for Reducing the Molecular Weight of Polypropylene Using Hydroxylamine Esters | CIBA SC HOLDING AG (CH) | 2006-05-10 | — | — | EP | disclosed |
| EP-1655303-A2 | Hydroxylamine esters as polimerization initiators | Ciba SC Holding AG (CH) | 2006-05-10 | — | — | EP | disclosed |
| US-7030196-B2 | Process for reducing the molecular weight of polypropylene | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-04-18 | — | — | US | disclosed |
| US-20030216494-A1 | Hydroxylamine esters as polymerization initiators | CIBA SPECIALTY CHEMICALS CORP. | 2003-11-20 | — | — | US | disclosed |
| EP-1282630-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | Ciba SC Holding AG (CH) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001090113-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216494-A1 | Hydroxylamine esters as polymerization initiators | PNMT, HPGDS, HAAO | SMN1; SMN2 4814/4885TSHR 2473/4885KMT2A 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.