Uric Acid

Uric Acid

SCHEMBL4325846

O=c1[nH]c(=O)c2[nH]c(=O)[nH]c2[nH]1.[LiH]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.94
ALDH1A1 P00352 4/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
HPGD P15428 2/20 0.46
CYP2C19 P33261 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 1/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
BRPF1 P55201 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TYMP P19971 5/20 0.39
GSK3B P49841 1/20 0.39
BACE1 P56817 1/20 0.39
IDH1 O75874 1/20 0.39
CSNK2A2 P19784 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uric Acid SCHEMBL3417988 0.97 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL22069923 0.97 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL7933 0.97 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL1071965 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL16213309 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL10631703 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL229866 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL196769 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL2434620 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL7020961 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226839-A1 SYSTEM AND PROCESS FOR RECLAIMING A METAL-CONTAINING SALT SOLUTION FROM A LITHIUM-CONTAINING BATTERY MATERIAL, AND CHEMICALS THEREOF eJoule, Inc. 2024-07-11 US claimed
CN-110434326-B Method for coating lithium aluminum oxide insulating layer on surface of metal soft magnetic powder in situ 浙江工业大学 2021-09-17 CN claimed
CN-110434326-A A kind of method of soft magnetic metal powder surface in-stiu coating lithium aluminum oxide insulating layer UNIV ZHEJIANG TECHNOLOGY 2019-11-12 CN claimed
US-20240226839-A1 SYSTEM AND PROCESS FOR RECLAIMING A METAL-CONTAINING SALT SOLUTION FROM A LITHIUM-CONTAINING BATTERY MATERIAL, AND CHEMICALS THEREOF eJoule, Inc. 2024-07-11 US disclosed
CN-110434326-B Method for coating lithium aluminum oxide insulating layer on surface of metal soft magnetic powder in situ 浙江工业大学 2021-09-17 CN disclosed
CN-110434326-A A kind of method of soft magnetic metal powder surface in-stiu coating lithium aluminum oxide insulating layer UNIV ZHEJIANG TECHNOLOGY 2019-11-12 CN disclosed
US-9913831-B2 Methods and compositions for treating nephrogenic diabetes insipidus UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2018-03-13 US disclosed
EP-2750676-B1 METHODS AND COMPOSITIONS FOR TREATING NEPHROGENIC DIABETES INSIPIDUS UNIV UTAH RES FOUND (US) 2018-01-10 EP disclosed
US-9539246-B2 Methods and compositions for treating nephrogenic diabetes insipidus UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2017-01-10 US disclosed
US-20160296504-A1 METHODS AND COMPOSITIONS FOR TREATING NEPHROGENIC DIABETES INSIPIDUS UNIVERSITY OF UTAH 2016-10-13 US disclosed
CN-105920605-A Application of anti-inositol metabolism medicament to establishment of mouse model with NTDs 王建华 2016-09-07 CN disclosed
US-8394121-B2 Intracardiac implant for delivery of alarmins and methods thereof W.L. GORE & ASSOCIATES, INC. (US) 2013-03-12 US disclosed
WO-2013033178-A1 METHODS AND COMPOSITIONS FOR TREATING NEPHROGENIC DIABETES INSIPIDUS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2013-03-07 WO disclosed
US-20090182372-A1 INTRACARDIAC IMPLANT FOR DELIVERY OF ALARMINS AND METHODS THEREOF W.L. GORE & ASSOCIATES, INC. 2009-07-16 US disclosed
US-20050037450-A1 Novel targets for lithium therapy DUKE UNIVERSITY 2005-02-17 US disclosed
WO-2004013152-A2 NOVEL TARGETS FOR LITHIUM THERAPY DUKE UNIVERSITY (US) 2004-02-12 WO disclosed
EP-0193061-B1 VIABILITY TEST DEVICE MILES INC. (US) 1990-01-03 EP disclosed
US-4683209-A Viability test device MILES LABORATORIES, INC. (US) 1987-07-28 US disclosed
US-4649121-A Viability test device MILES LABORATORIES, INC. (US) 1987-03-10 US disclosed
EP-0193061-A2 Viability test device MILES INC. (US) 1986-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160296504-A1 METHODS AND COMPOSITIONS FOR TREATING NEPHROGENIC DIABETES INSIPIDUS GPR119, SLC5A2, P2RY2 GDA 2414/4885ALDH1A1 2394/4885CYP1A2 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.