Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.83 |
| ▸ | DGKA | P23743 | 1/20 | 0.69 |
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | PAM | P19021 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396453 | 1.00 | DNM1 (0.83) | DNM1DGKANAAAPRSS1PRSS2 | |
| SCHEMBL10622058 | 1.00 | DNM1 (0.83) | DNM1DGKANAAAPRSS1PRSS2 | |
| SCHEMBL8397697 | 1.00 | DNM1 (0.83) | DNM1DGKANAAAPRSS1PRSS2 | |
| SCHEMBL8398143 | 1.00 | DNM1 (0.83) | DNM1DGKANAAAPRSS1PRSS2 | |
| SCHEMBL6849042 | 1.00 | DNM1 (0.83) | DNM1DGKANAAAPRSS1PRSS2 | |
| SCHEMBL4322849 | 1.00 | DNM1 (0.83) | DNM1DGKANAAAPRSS1PRSS2 | |
| SCHEMBL8394705 | 1.00 | DNM1 (0.83) | DNM1DGKANAAAPRSS1PRSS2 | |
| SCHEMBL13923753 | 1.00 | DNM1 (0.83) | DNM1DGKANAAAPRSS1PRSS2 | |
| SCHEMBL8397714 | 1.00 | DNM1 (0.83) | DNM1DGKANAAAPRSS1PRSS2 | |
| SCHEMBL1074804 | 0.98 | DNM1 (0.80) | DNM1DGKANAAAPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632869-B2 | Antimicrobial compositions and uses thereof | BAUSCH & LOMB INCORPORATED (US) | 2009-12-15 | — | — | US | claimed |
| EP-1748798-A1 | ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | BAUSCH & LOMB INCORPORATED (US) | 2007-02-07 | — | — | EP | claimed |
| WO-2005115485-A1 | ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | BAUSCH & LOMB INCORPORATED (US) | 2005-12-08 | — | — | WO | claimed |
| US-20050260099-A1 | Antimicrobial compositions and uses thereof | BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) | 2005-11-24 | — | — | US | claimed |
| US-7632869-B2 | Antimicrobial compositions and uses thereof | BAUSCH & LOMB INCORPORATED (US) | 2009-12-15 | — | — | US | disclosed |
| EP-1748798-A1 | ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | BAUSCH & LOMB INCORPORATED (US) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005115485-A1 | ANTIMICROBIAL COMPOSITIONS AND USES THEREOF | BAUSCH & LOMB INCORPORATED (US) | 2005-12-08 | — | — | WO | disclosed |
| US-20050260099-A1 | Antimicrobial compositions and uses thereof | BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050260099-A1 | Antimicrobial compositions and uses thereof | GSDMD, PHOSPHO1, MLEC | DNM1 260/4885DGKA 1231/4885NAAA 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.