SCHEMBL4326249

SCHEMBL4326249

Oc1c(-c2ccccc2)cc(-c2ccccc2)c(O)c1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.56
PDE4B Q07343 5/20 0.53
HDAC4 P56524 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
PDE4A P27815 4/20 0.48
PDE4C Q08493 4/20 0.48
PDE4D Q08499 4/20 0.48
PTPN1 P18031 3/20 0.48
ALOX5 P09917 1/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
BCL2L1 Q07817 1/20 0.48
HSD17B10 Q99714 1/20 0.48
HNF4A P41235 1/20 0.47
MAPT P10636 2/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
AKR1C3 P42330 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9469378 0.91 BACE1 (0.52) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL10338501 0.86 BACE1 (0.52) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL1524220 0.85 BACE1 (0.56) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL9469342 0.85 PDE4B (0.50) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL7634679 0.84 BACE1 (0.62) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL1760415 0.84 PDE4B (0.62) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL4647831 0.82 HDAC4 (0.54) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL29001722 0.81 PDE4B (0.58) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL8049995 0.81 BACE1 (0.46) BACE1PDE4BHDAC4HDAC2HDAC8
SCHEMBL9469023 0.80 PDE4B (0.42) BACE1PDE4BHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10436948-B2 Optical film, process for producing optical film, polarizer, and image display device FUJIFILM CORPORATION (JP) 2019-10-08 US disclosed
US-10240033-B2 Optical film and method for manufacturing same, polarization plate, and liquid crystal display apparatus FUJIFILM CORPORATION (JP) 2019-03-26 US disclosed
US-20160033687-A1 OPTICAL FILM, PROCESS FOR PRODUCING OPTICAL FILM, POLARIZER, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-02-04 US disclosed
US-20160033687-A1 OPTICAL FILM, PROCESS FOR PRODUCING OPTICAL FILM, POLARIZER, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-02-04 US disclosed
US-20150183977-A1 OPTICAL FILM AND METHOD FOR MANUFACTURING SAME, POLARIZATION PLATE, AND LIQUID CRYSTAL DISPLAY APPARATUS FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-20150183977-A1 OPTICAL FILM AND METHOD FOR MANUFACTURING SAME, POLARIZATION PLATE, AND LIQUID CRYSTAL DISPLAY APPARATUS FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
US-9013656-B2 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-9013656-B2 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-7615264-B2 Cellulose acylate film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2009-11-10 US disclosed
US-7615264-B2 Cellulose acylate film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2009-11-10 US disclosed
US-7611760-B2 Cellulose acylate film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2009-11-03 US disclosed
US-7611760-B2 Cellulose acylate film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2009-11-03 US disclosed
EP-2065425-A1 Method of producing polyether alcohols with DMC catalysts using special additives with aromatichydroxyl functionalisation Evonik Goldschmidt GmbH (DE) 2009-06-03 EP disclosed
CN-101445600-A Method of producing polyether alcohols with DMC catalysts using special additives with aromatichydroxyl functionalisation EVONIK GOLDSCHMIDT GMBH (DE) 2009-06-03 CN disclosed
US-20090137752-A1 Process for preparing polyether alcohols with DMC catalysts using specific additives with aromatic hydroxyl functionalization EVONIK GOLDSCHMIDT GMBH (DE) 2009-05-28 US disclosed