Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326249 | 0.91 | BACE1 (0.56) | BACE1PDE4BHDAC4HDAC2HDAC8 | |
| SCHEMBL28275162 | 0.85 | PDE4B (0.42) | BACE1PDE4BHDAC4HDAC2HDAC8 | |
| SCHEMBL1760415 | 0.84 | PDE4B (0.62) | BACE1PDE4BHDAC4HDAC2HDAC8 | |
| SCHEMBL10338501 | 0.82 | BACE1 (0.52) | BACE1PDE4BHDAC4HDAC2HDAC8 | |
| SCHEMBL1524220 | 0.81 | BACE1 (0.56) | BACE1PDE4BHDAC4HDAC2HDAC8 | |
| SCHEMBL9469342 | 0.81 | PDE4B (0.50) | BACE1PDE4BHDAC4HDAC2HDAC8 | |
| SCHEMBL7634679 | 0.80 | BACE1 (0.62) | BACE1PDE4BHDAC4HDAC2HDAC8 | |
| SCHEMBL9236954 | 0.80 | BACE1 (0.62) | BACE1PDE4BHDAC4HDAC2HDAC8 | |
| SCHEMBL20323159 | 0.78 | MMP3 (0.56) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4647831 | 0.78 | HDAC4 (0.54) | BACE1PDE4BHDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243016-A | Improved solubility, polyimides, polyether ketones, polyesters, polyether sulfones | HAY ALLAN S (CA) | 1993-09-07 | — | — | US | disclosed |
| US-5182358-A | Polyetherketones, polyethersulfone, polyetherimides, solubility in organic solvents | HAY ALLAN S (CA) | 1993-01-26 | — | — | US | disclosed |