Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | HK2 | P52789 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326249 | 0.85 | BACE1 (0.56) | PDE4BBACE1PDE4APDE4CPDE4D | |
| SCHEMBL9469378 | 0.81 | BACE1 (0.52) | PDE4BBACE1PDE4APDE4CPDE4D | |
| SCHEMBL8350739 | 0.80 | PTPN1 (0.56) | PDE4BBACE1HDAC4HDAC2HDAC8 | |
| SCHEMBL10338501 | 0.77 | BACE1 (0.52) | PDE4BBACE1PDE4APDE4CPDE4D | |
| SCHEMBL1524220 | 0.76 | BACE1 (0.56) | PDE4BBACE1PDE4APDE4CPDE4D | |
| SCHEMBL9329605 | 0.76 | KMT2A (0.41) | PDE4BBACE1PDE4APDE4CPDE4D | |
| SCHEMBL7634679 | 0.75 | BACE1 (0.62) | PDE4BBACE1ESR2HDAC4HDAC2 | |
| SCHEMBL1760415 | 0.75 | PDE4B (0.62) | PDE4BBACE1PDE4APDE4CPDE4D | |
| SCHEMBL9469704 | 0.75 | ESR2 (0.53) | PDE4BBACE1PDE4APDE4CPDE4D | |
| SCHEMBL27493715 | 0.74 | ESR2 (0.48) | PDE4BBACE1PDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243016-A | Improved solubility, polyimides, polyether ketones, polyesters, polyether sulfones | HAY ALLAN S (CA) | 1993-09-07 | — | — | US | disclosed |
| US-5182358-A | Polyetherketones, polyethersulfone, polyetherimides, solubility in organic solvents | HAY ALLAN S (CA) | 1993-01-26 | — | — | US | disclosed |